The R&D Dept.: Local patents for 5.29.19

Electronic prior authorization systems and methodologies
Patent No. 10,296,715
A method includes accessing from a predictive data mart at a cloud platform which contains historical data on prior authorization transactions, historical transaction data corresponding to information indicated to be necessary for authorization decisions by a payer for use of a proposed medication for treatment of a condition. The method further includes determining, based on the accessed historical transaction data, a most probable question set necessary for an authorization decision by the payer for use of the proposed medication for treatment of the condition.
Inventors: Stephen E. Smith (Richmond),Stanislav Makarskyy (Buffalo Grove, Ill.)
Assignee: Allscripts Software (Chicago, Ill.)
May 21, 2019

Manganese scavengers that minimize octane loss in aviation gasolines
Patent No. 10,294,435
Aviation gasolines and additives may have manganese-containing anti-knock components. The scavengers herein mitigate the possible deleterious effects from using the manganese-containing anti-knock. The scavengers include molecules with a central atom of a Group 15 element other than nitrogen. Entities that are attached to the central atom are electron withdrawing entities including electron deficient atoms and electron deficient functional groups.
Inventors: Joseph Anthony Calderone III (Powhatan, Va.), Zachary John McAfee (Richmond)
Assignee: Afton Chemical Corp. (Richmond)
May 21, 2019

E-vaping device cartridge with superabsorbent polymer
Patent No. 10,292,426
A cartridge for an e-vaping device includes a reservoir configured to hold pre-vapor formulation, a vaporizer assembly configured to draw at least some of the pre-vapor formulation from the reservoir and vaporize the drawn pre-vapor formulation to form a vapor, and a superabsorbent polymer configured to absorb free water from pre-vapor formulation held in the reservoir. The superabsorbent polymer includes a cross-linked polyacrylate copolymer that is substantially inert to the pre-vapor formulation. The superabsorbent polymer may be included in a layer on one or more surfaces in the cartridge. The layer may include the superabsorbent polymer and a binder. The superabsorbent polymer may be included with the pre-vapor formulation in a formulation mixture. The superabsorbent polymer may be included in an interior of at least one element comprising the cartridge. The superabsorbent polymer may be included in a separate compartment in the reservoir.
Inventors: Georgios Karles (Richmond), Erica Sena (Midlothian, Va.)
Assignee: Altria Client Services (Richmond)
May 21, 2019

System and method for cooking pieces of protein
Patent No. 10,292,409
A system for cooking pieces of protein may include a flour applicator that receives the pieces of protein in an uncooked state and applies a coating of flour to outer surfaces thereof; a batter applicator that receives the pieces of uncooked protein coated with the flour from the flour applicator and applies a batter made from high-gluten flour to the coated outer surfaces thereof; a packaging machine that receives the pieces of uncooked protein coated with the batter made from the high-gluten flour from the batter applicator and seals the pieces of protein in plastic pouches; and a heating unit that receives the sealed plastic pouches containing the uncooked protein coated with the batter from the packaging machine and cooks the battered protein pieces in the plastic pouches.
Inventors: Mark Auernheimer (Richmond), Zachary Shepard (Cincinnati, Ohio), Jeffrey D. Cowles (St. Simons Island, Ga.)
Assignee: Sugar Creek Packing Co. (Hamilton, Ohio)
May 21, 2019

High yielding tobacco with Oriental tobacco characteristics
Patent No. 10,292,352
This application provides high yielding tobacco plants with Oriental tobacco aroma and flavor characteristics and development of these plants via breeding. This application also provides hybrid seeds that give rise to high yielding tobacco plants with Oriental tobacco aroma and flavor characteristics. This application provides methods of growing and harvesting high yielding tobacco plants with Oriental tobacco aroma and flavor characteristics. This application further provides tobacco products made from high yielding tobacco plants with Oriental tobacco aroma and flavor characteristics, and methods making such tobacco products.
Inventors: Marcos Fernando de Godoy Lusso (Chesterfield, Va.), Greg Davis (Midlothian, Va.), Jerry W. Morris (Jetersville, Va.)
Assignee: Altria Client Services (Richmond, Va.)
May 21, 2019

Nicotiana nucleic acid molecules and uses thereof
Patent No. 10,294,520
The present invention features Nicotiana nucleic acid sequences such as sequences encoding constitutive, or ethylene or senescence induced polypeptides, in particular cytochrome p450 enzymes, in Nicotiana plants and methods for using these nucleic acid sequences and plants to alter desirable traits, for example by using breeding protocols.
Inventors: Dongmei Xu (Glen Allen, Va.), Mark T. Nielsen (Nicholasville, Ky.), Yanxin Shen (Glen Allen, Va.)
Assignee: U.S. Smokeless Tobacco Co. (Richmond)
May 21, 2019

Nicotiana nucleic acid molecules and uses thereof
Patent No. 10,292,416
The present invention features Nicotiana nucleic acid sequences such as sequences encoding constitutive, or ethylene or senescence induced polypeptides, in particular cytochrome p450 enzymes, in Nicotiana plants and methods for using these nucleic acid sequences and plants to alter desirable traits, for example by using breeding protocols.
Inventors: Dongmei Xu (Glen Allen, Va.), Mark T. Nielsen (Nicholasville, Ky.), Yanxin Shen (Glen Allen, Va.)
Assignee: Altria Client Services (Richmond)
May 21, 2019

Shaped heater for an aerosol generating system
Patent No. 10,306,707
A heater for heating an aerosol-forming substrate includes a plurality of elongate heating elements arranged in an elongate array. The elongate array has a support end with a first dimension, a heating end with a second dimension and a middle portion with a third dimension. The array is arranged to heat the substrate to form an aerosol. The third dimension is greater than the first dimension and greater than the second dimension. An electrically heated aerosol generating system can include the heater.
Inventors: Olivier Greim (Villars-Burquin,Switzerland), Felix Fernando (Berkshire, Great Britain), Charles Higgins (Richmond)
Assignee: Philip Morris USA Inc.. (Richmond)
May 28, 2019

Automated measurement of brain injury indices using brain CT images, injury data, and machine learning
Patent No. 10,303,986
A decision-support system and computer implemented method automatically measures the midline shift in a patient’s brain using Computed Tomography (CT) images. The decision-support system and computer implemented method applies machine learning methods to features extracted from multiple sources, including midline shift, blood amount, texture pattern and other injury data, to provide a physician an estimate of intracranial pressure (ICP) levels. A hierarchical segmentation method, based on Gaussian Mixture Model (GMM), is used. In this approach, first an Magnetic Resonance Image (MRI) ventricle template, as prior knowledge, is used to estimate the region for each ventricle. Then, by matching the ventricle shape in CT images to the MRI ventricle template set, the corresponding MRI slice is selected. From the shape matching result, the feature points for midline estimation in CT slices, such as the center edge points of the lateral ventricles, are detected. The amount of shift, along with other information such as brain tissue texture features, volume of blood accumulated in the brain, patient demographics, injury information, and features extracted from physiological signals, are used to train a machine learning method to predict a variety of important clinical factors, such as intracranial pressure (ICP), likelihood of success a particular treatment, and the need and/or dosage of particular drugs.
Inventors: Kayvan Najarian (Glen Allen, Va.), Wenan Chen (Richmond), Kevin R. Ward (Glen Allen, Va.)
Assignee: N/A
May 28, 2019

Flavor system and method for making beverages
Patent No. 10,301,583
A method of making a flavored beverage includes combining water and a plurality of flavor compounds in an amount sufficient to impart the flavor of a wine, a whiskey or a beer. A kit for making a flavored beverage can include a plurality of flavor compounds, a quantity of yeast, a quantity of sugar and a container.
Inventors: Christian Schuh (Chesterfield, Va.), Jason Flora (Richmond), Gerd Kobal (Sandy Hook, Va.), Georgios D. Karles (Richmond)
Assignee: Altria Client Services (Richmond)
May 28, 2019

Antistatic coated polyester film
Patent No. 10,301,483
An antistatic polyester film includes a self-supporting polyester substrate film bearing on at least one surface thereof an antistatic layer including a) one or more antistatic polymers comprising repeat units according to formula (I) wherein R.sup.1 and R.sup.2 are each independently H or CH.sub.3, R.sup.3 is an alkylene group having a carbon number in a range from 2 to 10, R.sup.4 and R.sup.5 are each independently a saturated hydrocarbon group having a carbon number in a range from 1 to 5, R.sup.6 is an alkylene group having a carbon number in a range from 2 to 5, n is an integer in a range from 0 to 40, m is an integer in a range from 1 to 40, and Y” is a halogen ion, nitrate ion, sulfate ion, alkylsulfate ion, sulfonate ion, alkylsulfonate ion or dihydrogen phosphate ion; b) one or more nonpolymeric cationic antistatic agents; and c) one or more crosslinkers. ##STR00001##
Inventors: Debra S. Strickland (Richmond), Julian Neal Robinson (Easby, Great Britain), Jackie H. Symonds (North Yorkshire, Great Britain), Cornell Chappell Jr. (Petersburg, Va.)
Assignee: DuPont Teijin Films U.S. LP (Chester, Va.)
May 28, 2019

Carton and blank therefor
Patent No. 10,301,091
A carton includes primary panels (12, 14, 16, 18) hingedly interconnected to form a tubular structure and an end closure structure (1). The primary panels include a first wall panel (12) and a second wall panel (14). The end closure structure includes a first end flap (22b) connected to the first wall panel and a second end flap (24b) connected to the second wall panel. The first end flap includes two arm portions (52, 54) each hingedly connected to the first wall panel, and a bridging portion (50) extending between the arm portions. The two arm portions are spaced apart from each other such that a display window (56) is defined between the two arm portions and that one or more containers (A) in the carton are exposed to view through the display window.
Inventors: Brandon L. Ramsuer (Henrico, Va.), Caleb S. Loftin (Richmond)
Assignee: WestRock Packaging Systems (Atlanta, Ga.)
May 28, 2019

Carton and carton blank
Patent No. 10,301,061
A carton for packaging one or more articles. The carton includes a plurality of panels for forming a tubular structure. The plurality of panels forming a tubular structure includes a first side wall panel, a first end wall panel, a second side wall panel; and second end wall panel. The carton includes a first handle structure defined in a first one of the plurality of panels. The first handle structure includes a severance line defining at least in part a handle opening. The carton includes a first end closure panel forming, at least in part, top wall which at least partially closes an upper end of the tubular structure and which is hingedly connected to the first one of the plurality of panels by a first hinged connection. The carton includes a first reinforcing flap hingedly connected to the first end closure panel by a second hinged connection. The second hinged connection is offset from the first hinged connection.
Inventors: Bradford J. Walling (Chesterfield, Va.), Ekaterina V. Gaidaeva (Richmond)
Assignee: WestRock Packaging Systems (Atlanta, Ga.)
May 28, 2019

Pod assembly, dispensing body, and e-vapor apparatus including the same
Patent No. 10,299,517
An e-vapor apparatus may include a pod assembly and a dispensing body configured to receive the pod assembly. A vaporizer may be disposed in the pod assembly and/or the dispensing body. The pod assembly may include a vapor precursor compartment, a device compartment, and a vapor channel extending from the device compartment and traversing the vapor precursor compartment. The pod assembly is a smart pod configured to receive, store, and transmit information that can be communicated with the dispensing body and/or another electronic device. The proximal portion of the dispensing body includes a vapor passage and a through-hole. The vapor passage may extend from an end surface of the proximal portion to a side wall of the through-hole. The through-hole is configured to receive the pod assembly such that the vapor channel of the pod assembly is aligned with the vapor passage of the dispensing body.
Inventors: Eric Hawes (Glen Allen, Va.), Raymond Lau (Richmond), Alistair Bramley (Richmond)
Assignee: Altria Client Services (Richmond)
May 28, 2019

Compound horizontal filter assembly machine and process
Patent No. 10,299,507
An apparatus and processes for producing compound cigarette filters by horizontally assembling multiple filter segments onto the horizontally oriented transverse flutes of a continuous belt. Spaced apart hoppers are serially arranged above the belt, and each hopper contains at least one of the multiple segments of the compound filter being assembled. A transfer structure between each hopper and the belt serially delivers the filter segments to the flutes on the belt, and after such assembly the various filter segments are removed as a group from each flute of the continuous belt. The filter segments are then combined as a group with wrapped tobacco rods to thereby produce filtered cigarettes.
Inventors: Michael S. Braunshteyn (Richmond), Raquel M. Olegario (Richmond)
Assignee: Philip Morris USA Inc. (Richmond)
May 28, 2019

Sweet taste modulators
Patent No. 10,301,275
Sweet taste modulators for enhancing sweetness of an oral consumer product having a sweetener are described. The sweet taste modulators include 5-ethoxymethyl-2-furaldehyde, 2,3-dihydroxybenzoic acid, 2,4-dihydroxybenzoic acid, 2,5-dihydroxybenzoic acid, 2,6-dihydroxybenzoic acid, 3,4-dihydroxybenzoic acid, 3,5-dihydroxybenzoic acid, 2,3,4-trihydroxybenzoic acid, 2,4,6-trihydroxybenzoic acid and 3,4,5-trihydroxybenzoic acid, syringic aldehyde, sinapic aldehyde, ester of 5-hydroxymethylfurfural and vanillic acid, 4-hydrozybenzaldehyde, and 5-methoxymethylfurfural. A method of making 5-ethoxymethyl-2-furaldehyde and a method of making an oral consumer product are also described.
Inventors: Andrea Froschmeier (Ingolstadt, Germany), Thomas Hofmann (Neufahn, Germany), Christian Schuh (Chesterfield, Va.)
Assignee: Altria Client Services (Richmond)
May 28, 2019

Systems and methods for offering products using linked transactions
Patent No. 10,304,083
The disclosed embodiments include methods, systems, and articles of manufacture for providing offers for linked transactions. Transaction data corresponding to a first product physically purchased using a financial service account and product identification data identifying the first purchased product are received. The transaction data and the product identification data are associated. A consumer that purchased the first product is determined based on at least the transaction data. Follow-on purchase to offer for sale to the consumer based on the product identification data is determined and a follow-up purchase offer to purchase the follow-on product is generated. The consumer is provided with the follow-on purchase offer to enable the consumer to purchase the follow-on product in an electronic commerce purchase transaction.
Inventors: Thomas S. Poole (Chantilly, Va.), David E. Keating (Glen Allen, Va.), Drew Jacobs (Arlington, Va.), Janusz M. Niczyporuk (Vienna, Va.), Luke A. Hammock (Washington, D.C.)
Assignee: Capital One Services (McLean, Va.)
May 28, 2019

Fiber comprising a mixture of poly(m-phenylene isophthalamide) and copolymer made from 5(6)-amino-2-(p-aminophenyl)benzimidazole
Patent No. 10,301,747
The invention concerns fiber, and a process for making same, the fiber comprising a mixture of at least a first polymer and a second polymer, the first polymer having a structure derived from the reaction of one or more amine monomers and a plurality of acid monomers, wherein the one or more amine monomers includes at least 60 mole percent 5(6)-amino-2-(p-aminophenyl)benzimidazole, and the plurality of acid monomers include those having a structure of Cl–CO–Ar.sub.1–CO–Cl and Cl–CO–Ar.sub.2–CO–Cl wherein Ar.sub.1 is an aromatic group having para-oriented linkages and Ar.sub.2 is an aromatic group having meta-oriented linkages, and wherein the plurality of acid monomers has at least 50 mole percent of the monomer containing aromatic group Ar.sub.2; and the second polymer has a structure derived from the reaction of metaphenylene diamine and isophthaloyl chloride. This fiber has use in heat-resistant protective apparel fabrics and garments.
Inventors: Kiu-Seung Lee (Midlothian, Va.)
Assignee: E I Du Pont De Nemours and Co. (Wilmington, Del.)
May 28, 2019

Composite sheet and cargo container comprising same
Patent No. 10,300,677
A non-rigid composite sheet comprising in order (i) a first component comprising at least one first fabric of continuous filament yarns having a tenacity of at least 11 g/dtex and a first polymeric layer, (ii) a second component comprising at least one second fabric of continuous filament glass yarns, the at least one second fabric being adjacent to the at least one first fabric of the first component, and (iii) a third component comprising a second polymeric layer.
Inventors: Dariusz Wlodzimierz Kawka (Midlothian, Va.)
Assignee: E I Du Pont De Nemours and Co. (Wilmington, Del.)
May 28, 2019

Organ protection solutions and method of use
Patent No. 10,300,029
An organ protectant solution which is intravenously administered includes at least one oncotic agent and optionally a high concentration of cell-impermeant molecules. Together, they promote transfer of water from cells to interstitium and into the capillaries, thereby preventing or reducing cell swelling, maintaining blood circulation and oxygenation of tissues, and extending the “Golden Hour” for traumatic and/or hemorrhagic shock patients. In addition, compositions comprising PEG-20k and methods of their use for preserving and/or reanimating harvested organs ex vivo for lengthy periods of time (e.g. at least about 8-24 hours) are also provided.
Inventors: Martin Mangino (Powhatan, Va.)
Assignee: Virginia Commonwealth University (Richmond)
May 28, 2019

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