The R&D Dept.: Local patents for 12.16.20

Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease
Patent No. 10,858,331
The invention provides new aromatic aldehyde compounds that have greater potency in increasing the affinity of Hb for oxygen, greater potency for preventing sickling, and additional pharmacologic properties that ameliorate other symptoms of SCD. The invention further provides methods for treating SCD by providing a subject having SCD with a compound according to the invention.
Inventors: Martin Safo (Richmond), Yan Zhang (Glen Allen, Virginia), Jurgen Venitz (Richmond), Richmond Danso-Danqua (Henrico, Virginia), Tanvi Deshpande (Somerville, Massachusetts)
Assignee: Virginia Commonwealth University (Richmond)
Dec. 8, 2020

Child-resistant package assembly
Patent No. 10,858,163
Disclosed are package assemblies and methods of making the same, wherein the assemblies can include, among other elements, an outer carton defining an interior product storage compartment; an inner product support card slidably received within the product storage compartment; the inner support card having a main body portion and one or more flaps; and one or more primary product packages, each being secured to one of the one or more flaps.
Inventors: Elizabeth A.Vercoe (Richmond), Marty Jones (Glen Allen, Virginia), Steven P. Jones (Elon, North Carolina)
Assignee: WestRock MWV (Atlanta, Georgia)
Dec.8, 2020

String filter
Patent No. 10,857,562
Example embodiments include a system for removing string from shredded tobacco, including an arrangement configured to dispense shredded tobacco from a first location to a second location along a path of communication, a string filter operative at a location along the path of communication comprising a first roller comprising pins, whereby string may be contacted by at least some of the pins and retained at the string filter as the shredded tobacco passes through the filter.
Inventors: Carl Patrick Kite (Midlothian, Virginia), Linwood Carneal (Richmond), Joshua Brock Craft (Chester, Virginia), Richard Kevin Barnhouse (Dinwiddie, Virginia)
Assignee: Altria Client Services (Richmond)
Dec. 8, 2020

System and method for applying a label for the automated production of e-vapor devices
Patent No. 10,858,137
A system for use in manufacturing vapor-generating articles may include a rotatable drum that is configured to hold a plurality of the vapor-generating articles. The system may also include a tagging drum that is configured to tag a respective label to a housing of each of the vapor-generating articles. The system may also include a pressing roller that is configured to press a leading edge of the label against the housing after the tagging. The system may further include a rolling drum that is configured to roll the label around the housing after the pressing.
Inventors: Martin Garthaffner (Chesterfield, Virginia)
Assignee: Altria Client Services (Richmond)
Dec. 8, 2020

One use wearable
Patent No. 10,861,004
Disclosed embodiments include methods, systems, and computer-readable media configured to, for example, provide payment tokens for conducting transactions, as well as reprovisioning tokens, on wearable devices without Bluetooth.RTM. or other network connectivity beyond NFC radio.
Inventors:  Lawrence Douglas (McLean, Virginia), Paul Moreton (Glen Allen, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Dec. 8, 2020

Systems and methods for cryptographic authentication of contactless cards
Patent No. 10,860,814
Example embodiments of systems and methods for data transmission between a contactless card and a receiving application are provided. The transmitting device may include a processor, memory, and communication interface. A receiving application may include instructions for execution on a receiving device having a processor, a memory, a communication interface configured to create a communication field for data communication with the transmitting device, and one or more sensors. Upon movement of the transmitting device, the receiving application is configured to receive, via one or more sensors, feedback information associated with the transmitting device, display one or more instructions regarding the position of the transmitting device relative to the receiving device until the transmitting device enters the communication field. Upon entry into the communication field, the transmitting device is configured to transmit data to the receiving device.
Inventors: Jeffrey Rule (Chevy Chase, Maryland), Daniel Herrington (New York, New York), Colin Hart (Arlington, Virginia), Kevin Osborn (Newton Highlands, Massachusetts), Melissa Heng (Glen Allen, Virginia), Rajko Ilincic (Annandale, Virginia), Jason Ji (Reston, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Dec. 8, 2020

Indirectly heated capillary aerosol generator
Patent No. 10,856,582
An indirectly heated capillary aerosol generator comprises a capillary tube adapted to form an aerosol when liquid material in the capillary tube is heated to volatilize at least some of the liquid material therein and a thermally conductive material in thermal contact with the capillary tube. The indirectly heated capillary aerosol generator provides substantially even and uniform heating across the heated length of the capillary tube.
Inventors: Marc D. Belcastro (Glen Allen, Virginia), Jeffrey A. Swepston (Powhatan, Virginia)
Assignee: Philip Morris USA (Richmond)
Dec. 8, 2020

Assessing user performance in a community of users of data storage resources
Patent No. 10,860,964
According to certain aspects, a method of assessing users of a data storage system can include receiving configuration information relating to a deployed configuration of a first data storage cell and including number of installed data storage hardware and/or software components, the first data storage cell comprising a plurality of client computing devices and being configured to create and store one or more secondary copies of primary data generated by the plurality of client computing devices. The method may also include receiving information relating to an incident opened by a user of the first data storage cell. The method may further include updating a performance metric associated with the user to a new value to reflect a negative impact on the performance metric resulting from the opening of the incident by the user, wherein the degree of the negative impact is based at least in part on the configuration information.
Inventors: Robert Keith Brower Jr. (Midlothian, Virginia), Peter John Messore (Manahawkin, New Jersey)
Assignee: Commvault Systems (Tinton Falls, New Jersey)
Dec. 8, 2020

Compositions and methods relating to DENND1A variant 2 and polycystic ovary syndrome
Patent No. 10,865,448
Provided are compositions and methods for use in polycystic ovary syndrome diagnosis (PCOS). The method involves a sample from a subject for a DENND1A Variant 2 mRNA or DENND1 A Variant 2 protein to make or aid in a diagnosis of PCOS. Also provided are methods for selecting an individual as a candidate for therapy for polycystic ovary syndrome by testing a biological sample from an individual for DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein and designating the individual as a candidate for the PCOS based on determining DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein in the sample. Also provided are products for use in aiding diagnosis of PCOS which contain reagents for detecting DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein, and packaging containing printed material describing use and indications for the product.
Inventors: Janette M. McAllister (Hummelstown, Pennsylvania), Jerome F. Strauss (Richmond)
Assignee: The Penn State Research Foundation (University Park, Pennsylvania) &
Virginia Commonwealth University (Richmond)
Dec. 15, 2020

Medication injection device with automatic needle retraction following injection
Patent No. 10,864,326
An automatic medication injection device including a driver (95), a retractor (190, 230) and a blocking member (180). Upon device triggering the driver is shifted proximally to move a device syringe, expel medication from the syringe0, and then to disengage itself from the syringe plunger. The driver and the blocking member have a complementary camming configuration by which the blocking member, during the driver shifting, is automatically rotated from a first rotational orientation to a second rotational orientation. The blocking member blocks retraction of the retractor when disposed in the first rotational orientation, and permits retraction of the retractor when disposed in the second rotational orientation, which retractor retraction withdraws the device syringe from an injecting position to a retracted position.
Inventors: Nicole Taylor Gonzalez (Indianapolis, Indiana), Gregory Alan Musselman (Hartford, Connecticut), Lisa Jeanne Nelson (Minneapolis, Minneapolis), Daniel Enluo Wang (Richmond)
Assignee: Eli Lilly and Co. (Indianapolis, Indiana)
Dec. 15, 2020

Blender jar assembly and associated blender
Patent No. 10,863,865
A blender jar assembly comprises a container portion having an open end for receiving the foodstuff to be blended and for dispensing the foodstuff after blending and a base portion selectively coupled to the container portion. The base portion comprises a floor and a sidewall connected to and extending from the floor to form a chamber for receiving at least a portion of the foodstuff during a blending operation. The chamber has an open end in fluid communication with the open end of the container portion when the container portion and the base portion are selectively coupled. The base further comprises one or more rotatable blades that are fully contained within the chamber formed by the floor and the sidewall and do not extend beyond a rim of the sidewall.
Inventors: Brian Bock (Midlothian, Virginia), David Matthew Schandel (Henrico, Virginia), Paul Diaz (Richmond), Benjamin H. Branson III (Mechanicsville, Virginia)
Assignee: Hamilton Beach Brands (Glen Allen, VA)
Dec. 15, 2020

Systems and methods for building generic CI/CD pipelines
Patent No. 10,866,793
At least one application may include instructions comprising application instructions and a plurality of separate pipeline definition instructions. The application instructions may be within a virtual container including at least one program that is generically executable in a plurality of different continuous integration and delivery (CI/CD) environments. Each of the plurality of separate pipeline definition instructions may be configured for each of the plurality of different CI/CD environments such that each pipeline definition may operate only in the CI/CD environment for which it is created. Each pipeline definition may be configured to cause the CI/CD environment for which it is created to execute the at least one program.
Inventors: Brandon Atkinson (Chesterfield, Virginia), Christopher Bowers (Midlothian, Virginia), Dallas Edwards (Midlothian, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Dec. 15, 2020

Auto-recovery for software systems
Patent No. 10,866,872
Disclosed are hardware and techniques for building runbooks for new computer-implemented processes by correlating break events from the new processes with break events extant in existing runbooks for existing computer-implemented processes. In addition, fix events associated with the correlated break events are evaluated to determine the likelihood that they will be able to fix the error condition which caused the break event from the new process. The fix events are presented to a human operator who may select and test each fix event to determine if the error condition is directed and, if so, the correlated break event associated with the fix event are merged together and added to a new runbook for the new computer-implement process.
Inventors: Bhavik Gudka (Glen Allen, Virginia), Milind Patel (Frisco, Texas), Surya Avirneni (Plano, Texas), Umang Mistry (Plano, Texas)
Assignee: Capital One Services (McLean, Virginia)
Dec. 15, 2020

Organophilic clays and drilling fluids containing them
Patent No. 10,865,338
The organophilic clay comprises a smectite-type clay ion exchanged with quaternary ammonium ions, where at least 75 mol-% of said quaternary ammonium ions are bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters and at least 90% of the fatty acid moieties of the bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters have a structure RC(O) with group R being a linear alkyl or alkenyl group containing from 9 to 21 carbon atoms. The organophilic clay is useful for thickening oil based compositions, in particular drilling fluids for drilling oil or gas wells, comprising an oil phase.
Inventors: Sarah Smith (Prince George, Virginia), Gary Davis (Westhampton, New Jersey), Dennis Parrish (Sandston, Virginia), Miyako Hisamoto (Glen Allen, Virginia)
Assignee: Evonik Corp. (Parsippany, New Jersey)
Dec. 15, 2020

Expansion module system
Patent No. 10,869,402
A system and approach that may connect communication modules together in a daisy chain fashion as an expansion bus. A communication module may be connected with a data bus and a voltage bus to a baseboard having a controller. The communication module may have a multi-port universal serial bus hub connected to the data bus from the expansion connector, an electronic device connected to the hub and the voltage regulator. Another communication module having a similar structure as the first communication module may be connected to the first communication module via a data bus between the multiport hub of the first expansion module and a universal serial bus hub of the other communication module, and may have a voltage bus connected to the voltage bus of the first communication module. More communication modules may be connected in a daisy chain or serial fashion to a preceding module, and so on.
Inventors: Jim Triplett (Midlothian, Virginia)
Assignee: Honeywell International Inc. (Morris Plains, New Jersey)
Dec. 15, 2020

Reinforced filtration apparatus
Patent No. 10,864,474
An illustrative aspect of the invention provides a filtration apparatus comprising a filtration element having a plurality of filtration media sheets and at least one reinforcement element positioned intermediate adjacent filtration media sheets. The reinforcement element has a body that is formed from a planar member having a plurality of apertures to allow passage of fluid therethrough. At least a portion of a surface of the reinforcement element is in contact with one of the filtration media sheets. At least a portion of another surface of the reinforcement element is in contact with the other filtration media sheet. Each of these surface portions defines a plane that is parallel to the filtration media sheet with which the surface portion is in contact.
Inventors: Chris Amey (Ashland, Virginia), Eric Duvekot (Ashland, Virginia), Paul Wilkinson (Fareham, Great Britain), Alun Williams (Fareham, Great Britain)
Assignee: Porvair Filtration Group Limited (Fareham, Great Britain)
Dec. 15, 2020

Targeted recall of semiconductor devices based on manufacturing data
Patent No. 10,867,877
A system for providing a targeted recall includes a metrology sub-system for performing in-line measurements on semiconductor dies after one or more fabrication steps to generate in-line measurement profiles, a failure analysis sub-system for determining a manufacturing fingerprint of a failed die, and a controller. The metrology sub-system may further perform one or more measurements of the semiconductor dies after one or more packaging steps to generate package characterization profiles. The controller may generate manufacturing fingerprints for the semiconductor dies based on the in-line measurement profiles and the package characterization profiles, which are referenced to unique electronic chip identifiers. The controller may further identify at-risk dies by comparing the manufacturing fingerprints of the semiconductor dies with the manufacturing fingerprint of the failed die and direct a targeted recall for the one or more at-risk dies.
Inventors: Robert J. Rathert (Mechanicsville, Virginia), David W. Price (Austin, Texas)
Assignee: KLA Corp. (Milpitas, California)
Dec. 15, 2020

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