The R&D Dept.: Local patents for 5.5.21

Methods and systems for detecting and quantifying peroxy acid and peroxide in fluids
Patent No. 10,989,699
Methods and systems are disclosed for analyzing and treating a fluid containing a peroxyacid and/or peroxide. A method of analyzing the fluid includes introducing into the fluid a decomposition agent that catalyzes decomposition of the peroxyacid and/or peroxide into decomposition products including oxygen, then directly or indirectly measuring an amount of oxygen produced after introduction of the decomposition agent, and determining an amount of the peroxyacid and/or peroxide present in the fluid. The amount of peroxyacid and/or peroxide in the fluid can also be monitored and controlled by further adjusting the amount of the peroxyacid and/or peroxide in the fluid based on the determined amount thereof. A system for performing the methods includes a decomposition agent infusion device for introducing the decomposition agent into a fluid sample, and a sensor for directly or indirectly measuring an amount of oxygen produced after introduction of the decomposition agent.
Inventors: John Richardson (Hanover, Virginia), Mark Puchovich (Henrico, Virginia), Benjamin Niemaseck (Richmond), Kevin White (Richmond), James Wilkins (Midlothian, Virginia), Robert Bedinger (Richmond)
Assignee: Chemtreat (Glen Allen, Virginia)
April 27, 2021

Methods for preparing therapeutically active cells using microfluidics
Patent No. 10,988,734
The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
Inventors: Anthony Ward (Rancho Santa Fe, California), Roberto Campos-Gonzalez (Carlsbad, California), Alison Skelley (Riverside, California), Khushroo Gandhi (Palo Alto, California), Curt Civin (Baltimore, Maryland), James C. Sturm (Princeton, New Jersey), Michael Grisham (Richmond)
Assignee: GPB Scientific (Richmond) & The Trustees of Princeton University (Princeton, New Jersey) & University of Maryland, Baltimore (Baltimore, Maryland)
April 27, 2021

Potent and selective mu opioid receptor modulators
Patent No. 10,988,481
Analogues of 6 .alpha./.beta.-naltrexamine (NAQ) are provided. The analogues are selective, reversible antagonists of the mu opioid receptor (MOR) that exhibit good blood brain barrier penetration. The compounds are used in the treatment of opioid addiction and other diseases and conditions, including for the treatment of pain.
Inventors: Yan Zhang (Richmond), Dana E. Selley (Richmond), William Dewey (Richmond), Hamid Abkarali (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
April 27, 2021

Systems and methods for controlling light in an incubator
Patent No. 10,987,269
The present disclosure provides for an incubator, which includes a film with a plurality of configurations. The configurations can include a first configuration to block the transmission of light through the film and a second configuration to be transparent to the transmission of light. The film can further allow any number of additional configurations with varying degrees of opacity, each opacity being between the opacities of the first and second configurations. The film can automatically change opacities based on input from an incubator processor or external devices configured to communicate with the incubator processor.
Inventors: Joshnamaithili Seelam (Richmond), Aniket Kulkarni (Glen Allen, Virginia), Kashyap Venuthurupalli (Ashburn, Virginia), Chandana Muktipaty (Glen Allen, Virginia)
Assignee: Kilo Medical Solutions (Richmond)
April 27, 2021

Charger assembly and charging system for an electronic vaping device
Patent No. 10,986,876
A charger assembly is configured to charge the electronic vaping device. The charger assembly includes a base including a housing defining a port. The port is configured to receive a tip end of an electronic vaping device. The port includes a magnetic electrical contact centrally positioned at a bottom of the port and a first pin positioned at the bottom of the port. The charger assembly also includes a microprocessor electrically connected to the magnetic electrical contact and the first pin.
Inventors: Geoffrey Brandon Jordan (Midlothian, Virginia), Barry S. Smith (Hopewell, Virginia), Douglas A. Burton (Glen Allen, Virginia), Eric Hawes (Glen Allen, Virginia), Sean Sundberg (Richmond), Berina Yerkic-Husejnovic (Richmond)
Assignee: Altria Client Services (Richmond)

Non-combustible smoking systems, devices and elements thereof
Patent No. 10,986,874
At least one example embodiment provides a non-combustible smoking system or kit, comprising: a cartridge having a first end and a second end; and a tobacco containing section having a third end and a fourth end. The cartridge includes: a pre-vapor formulation reservoir element and a pre-vapor heating element coupled to the pre-vapor formulation reservoir element. The tobacco containing section includes a tobacco housing and a tobacco heating element. The first end of the cartridge is configured to be connected to the fourth end of the tobacco containing section, and the second end of the cartridge is configured to be connected to the third end of the tobacco containing section.
Inventors: Christopher S. Tucker (Midlothian, Virginia), Barry Smith (Hopewell, Virginia), Ed Cadieux (Mechanicsville, Virginia), David Bennett (Richmond), Raquel Olegario (Richmond), San Li (Midlothian, Virginia), Georgios Karles (Richmond), Richard Jupe (Richmond), Peter Lipowicz (Midlothian, Virginia), Benjamin Ragland (Providence Force, Virginia)
Assignee: Altria Client Services (Richmond)
April 27, 2021

Organoboranes useful as electrolytes for lithium batteries
Patent No. 10,988,489
Disclosed are novel organoborane compositions of Formula (I), (II) or (III), ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R’, R”, n, n’, n”, m, m’, and m” are defined hereinabove. Also disclosed is a method of using said compositions for electrolytic media in lithium rechargeable batteries, including lithium-ion or lithium-air rechargeable batteries. Also disclosed are compositions containing said Formula (I), (II) and (III) compounds with lithium salts, useful as electrolytic media or matrices.
Inventors: Ishrat Khan (Marietta, Georgia), Ahmed Alzharani (Glen Allen, Virginia), Amal Al-abdulrahman (Atlanta, Georgia), Rasha Alshahrani (Abha, Saudi Arabia)
Assignee: Clark Atlanta University (Atlanta, Georgia)
April 27, 2021

Doubly-separating explosively releasable bolt
Patent No. 10,989,243
An explosive bolt is provided for securing a brace in tension. The bolt includes a bar, a pair of explosives, a pair of detonators and a pair of anchors. The bar has opposing longitudinal ends and an outer thickness. Opposing bores extend inwardly from the longitudinal ends to corresponding depth ends. First and second notches reduce the thickness proximate to the corresponding depth ends. A center rod separates the notches from each other. Each explosive correspondingly inserts into a corresponding bore to a corresponding depth end. Each detonator correspondingly inserts into the corresponding bore. Each anchor secures the bar to the brace. In further embodiments, the longitudinal ends include helical male threads, and the anchors are nuts having helical female threads.
Inventors: Myron L. Thomas (King George, Virginia), Seth Leland Williamson (King George, Virginia), Joshua Geiger Clarke (Ashland, Virginia), Logan M. Compton (Fredericksburg, Virginia)
Assignee: United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
April 27, 2021

Method and system for performing a financial transaction using a user interface
Patent No. 10,997,572
A system and method for performing a financial transaction by determining a master account number associated with one or more accounts that a user may access, providing data to generate a user interface displaying a list of the accounts and an indicator associated with a financial transaction, receiving indicator information associating the indicator with one or more of the accounts, receiving terms for the financial transaction, and performing the financial transaction. The list of accounts may be expanded to view account information.
Inventors: Elizabeth E. Cole (Washington, D.C.), Julio Farach (Atlanta, Georgia), Jill Sorg (Richmond), Donald Jeffrey Smith (Richmond), Hector Crespo (Frisco, Texas), Lynn Jackson (Denton, Texas)
Assignee: Capital One Services (McLean, Virginia)
May 4, 2021

Devices and methods for repairing damage to a nerve
Patent No. 10,994,130
An example device for repairing a nerve is described herein. The device can include a flexible carrier layer made of a biologic material, and a metallic support member including a plurality of micro-protrusions extending therefrom. The metallic support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the nerve, and the micro-protrusions can be configured to attach to a superficial tissue of the nerve.
Inventors: Isaac Perry Clements (Marietta, Georgia), Andrew Willsie (Lilburn, Georgia), James David Ross (Decatur, Georgia), Alex Weidenbach (Atlanta, Georgia), Jonathan Isaacs (Richmond)
Assignee: BioCircuit Technologies (Atlanta, Georgia) & Virginia Commonwealth University (Richmond)
May 4, 2021

Systems and methods for providing predictive quality analysis
Patent No. 10,996,943
The disclosed embodiments include methods and systems for providing predictive quality analysis. Consistent with disclosed embodiments, a system may receive input data associated with a software program and compare the input data with one or more predetermined analysis parameters. The system may further determine at least one risk rating based on the comparison, wherein each risk rating corresponds to a distinct software category. The system may perform additional operations, including determining at least one adjustment to the software program based on the determined at least one risk rating, and prioritizing the at least one adjustment based on a predetermined adjustment priority standard. Furthermore, the system may provide a report including at least an indication of the at least one prioritized adjustment, a timeline for implementing the at least one prioritized adjustment, and plan implementing the at least one prioritized adjustment.
Inventors: Jyoti Bhardwaj (Glen Allen, Virginia)
Assignee: Capital One Services (McLean, Virginia)
May 4, 2021

Electronic vaping device with tubular heating element
Patent No. 10,994,086
A cartridge of an electronic vaping device includes a reservoir configured to store a pre-vapor formulation and a heating element configured to heat the pre-vapor formulation. The heating element includes a metal tube having a first end and a second end. The metal tube defines an opening therethrough. The metal tube includes a sidewall defining at least one spiral channel extending substantially continuously along a portion of the metal tube.
Inventors: Travis Martin Garthaffner (Midlothian, Virginia), Charles L. Dendy (Ruther Glen, Virginia)
Assignee: Altria Client Services (Richmond)
May 4, 2021

Spray device and methods for making the same
Patent No. 10,994,295
A spray device includes a spray closure (100) attached to a container (900), the spray closure (100) having an air intake and a fluid intake into a mixing chamber (150) where the air and fluid are mixed before exiting an orifice (130), the air intake connected to a snorkel (120) for delivering air from within the container (900) into the mixing chamber (150).
Inventors: Brandon L. Ramsuer (Henrico, Virginia)
Assignee: Silgan Dispensing Systems Corp. (Grandview, Missouri)
May 4, 2021

Methods and systems for detecting and quantifying peroxy acid and peroxide in fluids
Patent No. 10,989,699
Methods and systems are disclosed for analyzing and treating a fluid containing a peroxyacid and/or peroxide. A method of analyzing the fluid includes introducing into the fluid a decomposition agent that catalyzes decomposition of the peroxyacid and/or peroxide into decomposition products including oxygen, then directly or indirectly measuring an amount of oxygen produced after introduction of the decomposition agent, and determining an amount of the peroxyacid and/or peroxide present in the fluid. The amount of peroxyacid and/or peroxide in the fluid can also be monitored and controlled by further adjusting the amount of the peroxyacid and/or peroxide in the fluid based on the determined amount thereof. A system for performing the methods includes a decomposition agent infusion device for introducing the decomposition agent into a fluid sample, and a sensor for directly or indirectly measuring an amount of oxygen produced after introduction of the decomposition agent.
Inventors: John Richardson (Hanover, Virginia), Mark Puchovich (Henrico, Virginia), Benjamin Niemaseck (Richmond), Kevin White (Richmond), James Wilkins (Midlothian, Virginia), Robert Bedinger (Richmond)
Assignee: Chemtreat (Glen Allen, Virginia)
April 27, 2021

Methods for preparing therapeutically active cells using microfluidics
Patent No. 10,988,734
The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
Inventors: Anthony Ward (Rancho Santa Fe, California), Roberto Campos-Gonzalez (Carlsbad, California), Alison Skelley (Riverside, California), Khushroo Gandhi (Palo Alto, California), Curt Civin (Baltimore, Maryland), James C. Sturm (Princeton, New Jersey), Michael Grisham (Richmond)
Assignee: GPB Scientific (Richmond) & The Trustees of Princeton University (Princeton, New Jersey) & University of Maryland, Baltimore (Baltimore, Maryland)
April 27, 2021

Potent and selective mu opioid receptor modulators
Patent No. 10,988,481
Analogues of 6 .alpha./.beta.-naltrexamine (NAQ) are provided. The analogues are selective, reversible antagonists of the mu opioid receptor (MOR) that exhibit good blood brain barrier penetration. The compounds are used in the treatment of opioid addiction and other diseases and conditions, including for the treatment of pain.
Inventors: Yan Zhang (Richmond), Dana E. Selley (Richmond), William Dewey (Richmond), Hamid Abkarali (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
April 27, 2021

Systems and methods for controlling light in an incubator
Patent No. 10,987,269
The present disclosure provides for an incubator, which includes a film with a plurality of configurations. The configurations can include a first configuration to block the transmission of light through the film and a second configuration to be transparent to the transmission of light. The film can further allow any number of additional configurations with varying degrees of opacity, each opacity being between the opacities of the first and second configurations. The film can automatically change opacities based on input from an incubator processor or external devices configured to communicate with the incubator processor.
Inventors: Joshnamaithili Seelam (Richmond), Aniket Kulkarni (Glen Allen, Virginia), Kashyap Venuthurupalli (Ashburn, Virginia), Chandana Muktipaty (Glen Allen, Virginia)
Assignee: Kilo Medical Solutions (Richmond)
April 27, 2021

Charger assembly and charging system for an electronic vaping device
Patent No. 10,986,876
A charger assembly is configured to charge the electronic vaping device. The charger assembly includes a base including a housing defining a port. The port is configured to receive a tip end of an electronic vaping device. The port includes a magnetic electrical contact centrally positioned at a bottom of the port and a first pin positioned at the bottom of the port. The charger assembly also includes a microprocessor electrically connected to the magnetic electrical contact and the first pin.
Inventors: Geoffrey Brandon Jordan (Midlothian, Virginia), Barry S. Smith (Hopewell, Virginia), Douglas A. Burton (Glen Allen, Virginia), Eric Hawes (Glen Allen, Virginia), Sean Sundberg (Richmond), Berina Yerkic-Husejnovic (Richmond)
Assignee: Altria Client Services (Richmond)

Non-combustible smoking systems, devices and elements thereof
Patent No. 10,986,874
At least one example embodiment provides a non-combustible smoking system or kit, comprising: a cartridge having a first end and a second end; and a tobacco containing section having a third end and a fourth end. The cartridge includes: a pre-vapor formulation reservoir element and a pre-vapor heating element coupled to the pre-vapor formulation reservoir element. The tobacco containing section includes a tobacco housing and a tobacco heating element. The first end of the cartridge is configured to be connected to the fourth end of the tobacco containing section, and the second end of the cartridge is configured to be connected to the third end of the tobacco containing section.
Inventors: Christopher S. Tucker (Midlothian, Virginia), Barry Smith (Hopewell, Virginia), Ed Cadieux (Mechanicsville, Virginia), David Bennett (Richmond), Raquel Olegario (Richmond), San Li (Midlothian, Virginia), Georgios Karles (Richmond), Richard Jupe (Richmond), Peter Lipowicz (Midlothian, Virginia), Benjamin Ragland (Providence Force, Virginia)
Assignee: Altria Client Services (Richmond)
April 27, 2021

Organoboranes useful as electrolytes for lithium batteries
Patent No. 10,988,489
Disclosed are novel organoborane compositions of Formula (I), (II) or (III), ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R’, R”, n, n’, n”, m, m’, and m” are defined hereinabove. Also disclosed is a method of using said compositions for electrolytic media in lithium rechargeable batteries, including lithium-ion or lithium-air rechargeable batteries. Also disclosed are compositions containing said Formula (I), (II) and (III) compounds with lithium salts, useful as electrolytic media or matrices.
Inventors: Ishrat Khan (Marietta, Georgia), Ahmed Alzharani (Glen Allen, Virginia), Amal Al-abdulrahman (Atlanta, Georgia), Rasha Alshahrani (Abha, Saudi Arabia)
Assignee: Clark Atlanta University (Atlanta, Georgia)
April 27, 2021

Doubly-separating explosively releasable bolt
Patent No. 10,989,243
An explosive bolt is provided for securing a brace in tension. The bolt includes a bar, a pair of explosives, a pair of detonators and a pair of anchors. The bar has opposing longitudinal ends and an outer thickness. Opposing bores extend inwardly from the longitudinal ends to corresponding depth ends. First and second notches reduce the thickness proximate to the corresponding depth ends. A center rod separates the notches from each other. Each explosive correspondingly inserts into a corresponding bore to a corresponding depth end. Each detonator correspondingly inserts into the corresponding bore. Each anchor secures the bar to the brace. In further embodiments, the longitudinal ends include helical male threads, and the anchors are nuts having helical female threads.
Inventors: Myron L. Thomas (King George, Virginia), Seth Leland Williamson (King George, Virginia), Joshua Geiger Clarke (Ashland, Virginia), Logan M. Compton (Fredericksburg, Virginia)
Assignee: United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
April 27, 2021

Method and system for performing a financial transaction using a user interface
Patent No. 10,997,572
A system and method for performing a financial transaction by determining a master account number associated with one or more accounts that a user may access, providing data to generate a user interface displaying a list of the accounts and an indicator associated with a financial transaction, receiving indicator information associating the indicator with one or more of the accounts, receiving terms for the financial transaction, and performing the financial transaction. The list of accounts may be expanded to view account information.
Inventors: Elizabeth E. Cole (Washington, D.C.), Julio Farach (Atlanta, Georgia), Jill Sorg (Richmond), Donald Jeffrey Smith (Richmond), Hector Crespo (Frisco, Texas), Lynn Jackson (Denton, Texas)
Assignee: Capital One Services (McLean, Virginia)
May 4, 2021

Devices and methods for repairing damage to a nerve
Patent No. 10,994,130
An example device for repairing a nerve is described herein. The device can include a flexible carrier layer made of a biologic material, and a metallic support member including a plurality of micro-protrusions extending therefrom. The metallic support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the nerve, and the micro-protrusions can be configured to attach to a superficial tissue of the nerve.
Inventors: Isaac Perry Clements (Marietta, Georgia), Andrew Willsie (Lilburn, Georgia), James David Ross (Decatur, Georgia), Alex Weidenbach (Atlanta, Georgia), Jonathan Isaacs (Richmond)
Assignee: BioCircuit Technologies (Atlanta, Georgia) & Virginia Commonwealth University (Richmond)
May 4, 2021

Systems and methods for providing predictive quality analysis
Patent No. 10,996,943
The disclosed embodiments include methods and systems for providing predictive quality analysis. Consistent with disclosed embodiments, a system may receive input data associated with a software program and compare the input data with one or more predetermined analysis parameters. The system may further determine at least one risk rating based on the comparison, wherein each risk rating corresponds to a distinct software category. The system may perform additional operations, including determining at least one adjustment to the software program based on the determined at least one risk rating, and prioritizing the at least one adjustment based on a predetermined adjustment priority standard. Furthermore, the system may provide a report including at least an indication of the at least one prioritized adjustment, a timeline for implementing the at least one prioritized adjustment, and plan implementing the at least one prioritized adjustment.
Inventors: Jyoti Bhardwaj (Glen Allen, Virginia)
Assignee: Capital One Services (McLean, Virginia)
May 4, 2021

Electronic vaping device with tubular heating element
Patent No. 10,994,086
A cartridge of an electronic vaping device includes a reservoir configured to store a pre-vapor formulation and a heating element configured to heat the pre-vapor formulation. The heating element includes a metal tube having a first end and a second end. The metal tube defines an opening therethrough. The metal tube includes a sidewall defining at least one spiral channel extending substantially continuously along a portion of the metal tube.
Inventors: Travis Martin Garthaffner (Midlothian, Virginia), Charles L. Dendy (Ruther Glen, Virginia)
Assignee: Altria Client Services (Richmond)
May 4, 2021

Spray device and methods for making the same
Patent No. 10,994,295
A spray device includes a spray closure (100) attached to a container (900), the spray closure (100) having an air intake and a fluid intake into a mixing chamber (150) where the air and fluid are mixed before exiting an orifice (130), the air intake connected to a snorkel (120) for delivering air from within the container (900) into the mixing chamber (150).
Inventors: Brandon L. Ramsuer (Henrico, Virginia)
Assignee: Silgan Dispensing Systems Corp. (Grandview, Missouri)
May 4, 2021

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