The R&D Dept.: Local patents for 9.8.21

Data management system and method
Patent No. 1,108,674
Aspects of the present disclosure are directed to electronic computer implemented methods of data communication. The method may include via a computer-based originating data communication network, receiving a smart data payload including an originating node attribute, an injectable tracking attribute and at least one data element associated with a computer readable record; electronically processing the smart data payload including the ID attribute, the injectable tracking attribute and the at least one data element associated; electronically extracting the injectable tracking attribute to determine a network location and electronically transmitting a data element associated with injectable tracking attribute to the originating data communication network for storage in a computer readable database.
Inventors: Kevin A. Delson (Woodland Hills, California), Ronald D. Hooper (Charlotte, North Carolina), Manu Kurian (Dallas, Texas), Megan Kelly (Richmond)
Assignee: Bank of America Corp. (Charlotte, North Carolina)
Aug. 31, 2021

Electrolytes containing superhalogens for metal ion batteries
Patent No. 11,108,087
Compounds (salts) for use as electrolytes, e.g. in batteries such as Li ion, Na ion and Mg ion batteries are provided. The negative ions (anions) of the compounds are complex molecules containing superhalogens, and thus exhibit improved safety, and yet have electron affinities that are equal to or greater than those of halogens. In addition, the binding energy between Li+ and the anions is relatively small so ions can move easily from one electrode to the other in solutions in which the compounds are dissolved. A further advantage is that the affinity of the electrolyte for water is also relatively low so that batteries in which the electrolytes are used have longer lives than those of the prior art.
Inventors: Jena Purusottam (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Aug. 31, 2021

Systems and methods for merging a virtual world, live events and an entertainment channel
Patent No. 11,107,105
Systems, methods and software merge a Virtual World, Live Event and Entertainment Channel, thus creating “The Perfect Storm” of gaming and entertainment whereby the characters of a social network game (e.g., an online fantasy sports league) are represented by human beings who register to be avatars of characters supported by a “Character Service Center,” while players compete to bring avatars to life in a Real World event (e.g., a Real World sports league), where the human beings behind the avatars compete for prizes while staying in character, as these competitors and players are incentivized by a “Collaboration Incentive Platform.”
Inventors: Kenneth Lloyd Tayloe (Los Angeles, California), Paul Howard Glass (Westlake Village, California), David Eugene Williamson Jr. (Richmond), Jordan William Snider (Los Angeles, California)
Assignee: MWE Live (Hermosa Beach, California)
Aug. 31, 2021

Fuzzy search of graph database
Patent No. 11,106,736
A method may compiling, using at least one processor, a corpus of training data by obtaining, for each respective concept object in an ontology, a respective concept label and respective annotations describing the respective concept object; generating a vocabulary of terms based on the corpus of training data; training a semantic model using the corpus of training data and the vocabulary of terms, wherein input features for the semantic model are based on context words in proximity to a term in the vocabulary of terms; and storing a set of word embeddings for the vocabulary of terms based on the trained semantic model.
Inventors: David Newman (Walnut Creek, California), Omar B. Khan (Richmond), Nathan Anthony Susanj (York, Pennsylvania), Alexander Joseph Kalinowski (Philadelphia, Pennsylvania)
Assignee: Wells Fargo Bank (San Francisco, California)

Extruded mat
Patent No. 11,105,099
A drainage component having a continuous, extruded mat having an upper face and a lower face. The mat includes a plurality of patterned three-dimensional structures, each structure spaced from all adjacent structures, and the plurality of patterned three-dimensional structures are provided in a plurality of linear rows or columns in a first direction.
Inventors: Lori C. Hascher (Candler, North Carolina), James E. Mathis (Candler, North Carolina), W. Allan Wingfield (Candler, North Carolina), Wazir Nobbee (Richmond), Rupa Kibbe (Wilmington, Delaware)
Assignee: Low & Bonar (Candler, North Carolina)
E.I. Du Pont de Nemours and Co. (Wilmington, Delaware)
Aug. 31, 2021

Compositions and methods for producing tobacco plants and products having reduced or eliminated suckers
Patent No. 11,104,912
The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
Inventors: Dongmei Xu (Glen Allen, Virginia), Jesse Frederick (Richmond), Chengalrayan Kudithipudi (Midlothian, Virginia), Yanxin Shen (Glen Allen, Virginia), James Strickland (Richmond), Jaemo Yang (Richmond)
Assignee: Altria Client Services (Richmond)
Aug. 31, 2021

Metabolically stable vanillin derivatives for the treatment of hypoxia
Patent No. 11,104,632
Vanillin derivative compounds that bind covalently with hemoglobin are provided. Methods of treating sickle cell disease and other hypoxia-related disorders by administering such compounds are also provided.
Inventors: Abdelsattar Mansour Ebeid Omar (Jeddah, Saudi Arabia), Moustafa El-Sayed El-Araby (Jeddah, Saudi Arabia), Martin K. Safo (Richmond)
Assignee: King Abdulaziz University (Jeddah, Saudi Arabia) & Virginia Commonwealth University (Richmond)
Aug. 31, 2021

Product portion enrobing machines and methods
Patent No. 11,103,002
An apparatus for enrobing a product portion can include at least one polymer spray head adapted to create at least one flow of polymeric fibers to produce at least one polymer enrobing zone and a conveyor system adapted to move at least one product portion from at least one position below at least one polymer enrobing zone and to at least one position above at least one polymer enrobing zone to drop each product portion through one or more polymer enrobing zones a plurality times at different orientations to enrobe each product portion with polymeric fibers.
Inventors: Andrew Nathan Carroll (Chester, Virginia), Shannon Maxwell Black (Richmond), Yan Helen Sun (Midlothian, Virginia), William J. Burke (Nashville, Tennessee), Robert Smith (Glen Allen, Virginia)
Assignee: Altria Client Services (Richmond)
Aug. 31, 2021

Patient identification systems and methods
Patent No. 11,106,818
Systems and methods for managing patient information across various electronic medical record (EMR) systems, according to some examples can involve providing a patient information management system having a cloud-based application server including a database, a client application interface and a mobile security token. A one-time verification code can be sent from the cloud-based application server to the client computing device and read using the mobile security token. The mobile security token can be matched to a patient demographic record in the database to authenticate the patient using the linked mobile security token.
Inventors: David Batchelor (Newcastle, California), Catherine Schulten (Chesterfield, Virginia), Elvar H. Olafsson (Roseville, California)
Assignee: LifeMed ID (Citrus Heights, California)
Aug. 31, 2021

LED sleeve for emergency breathing safety system connection
Patent No. 11,107,341
An air supply indicator apparatus for indicating an amount of breathing air remaining in a cylinder, the apparatus including a housing member having a first side integrally formed with an attachment member, the attachment member configured to be detachably coupled to an emergency breathing safety system (EBSS) or universal emergency breathing safety system (UEBBS) and a second side form with an enclosure, an air status management status indicator having a plurality of indicator light sources disposed on the housing member, and a processor disposed within the enclosure, the processor coupled to the air status management status indicator and configured to emit light from the plurality of indicator light sources based on received signals corresponding to an amount of air remaining in a cylinder.
Inventors: Jamie Little (Midlothian, Virginia)
Assignee: N/A
Aug. 31, 2021

.sup.18F-labeled compounds for PET imaging and uses thereof
Patent No. 11,103,603
The present invention relates to .sup.18F-labeled compounds suitable for positron emission tomography (PET) imaging. The invention further relates to the use of these compounds for carrying out PET scans, imaging the indoleamine 2,3-dioxygenase, pathway, predicting the responsiveness of a subject with a solid tumor to therapies including immunotherapy such as PD-1/PD-L1 inhibition, and determining whether a solid tumor in a subject contains tumor-infiltrating immune cells.
Inventors: Zibo Li (Chapel Hill, North Carolina), Zhanhong Wu (Chapel Hill, North Carolina), Ben Giglio (Henrico, Virginia), Stergios Moschos (Durham, North Carolina)
Assignee: The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
Aug. 31, 2021

Model-based promotion and price computation system and method
Patent No. 11,113,710
A system and method for providing model-based promotion and price computation is described in which promotional offers in the form of promotion information from a manufacturer are combined with price determination parameters from the retailer to calculate a final retail price. The system prevents fraud by eliminating the heavy dependence on unverifiable trust between the retailer and manufacturer and by assuring that the consumer will receive the benefit of the promotions intended by the manufacturer.
Inventors: William R. Sweeney (Richmond)
Assignee: Philip Morris USA (Richmond)
Sept. 7, 2021

Glutamine antagonists for the treatment of cognitive deficits and psychiatric disorders
Patent No. 11,110,104
The disclosure provides compounds having formula (I): ##STR00001## and the pharmaceutically acceptable salts thereof, wherein R.sub.1, R.sub.2, R.sub.2′, and X are as defined as set forth in the specification, for use in treating cognitive deficits and/or psychiatric disorders, such as those associated with neurological or neurodegenerative disorders, psychiatric or mood disorders, and HIV-associated neurocognitive disorders (HAND). Compounds having formula (I) are prodrugs that release glutamine analogs, e.g., 6-diazo-5-oxo-L-norleucine (DON).
Inventors: Barbara Slusher (Kingsville, Maryland), David Volsky (Scarsdale, New York), Mike Nedelcovych (Richmond), Kristen Hollinger (Parkton, Maryland), Atsushi Kamiya (Pikesville, Maryland)
Assignee: The Johns Hopkins University (Baltimore, Maryland) & Icahn School of Medicine at Mount Sinai (New York, New York)
Sept. 7, 2021

Knowledge-based decision support systems and method for process lifecycle automation
Patent No. 11,113,640
Computer implemented knowledge-based decision support system and method is provided. The method includes registering one or more software applications and data sources; defining processes to be implemented by executing the registered one or more software applications; orchestrating execution of the registered one or more software applications for implementing the processes; monitoring system performance based on the execution of the registered one or more software applications; generating analytics data related to the monitored system performance; updating a database with historical data using the generated analytics data; generating an analytical report by analyzing, using a machine learning technique, the historical data stored in the database as well as the generated analytics data; generating automatically user interface based on at least one of a layout and a specification provided by a user; modifying execution of the registered one or more software applications based on the generated analytical report; and displaying data from the generated analytical report using the user interface.
Inventors: Sreedhar Chintalapaty (Frisco, Texas), Seekar Ghodgaonkar (Glen Allen, Virginia), Dhamodararaj Kannan (Round Rock, Texas), Aashish Chandra (Fremont, California)
Assignee: Tata Consultancy Services Limited (Mumbai, India)
Sept. 7, 2021

Deactivation wipe kit
Patent No. 11,111,466
A hazardous drug deactivation wipe kit includes a first pouch having a one-way valve coupled to an end thereof, a second pouch, and a third pouch. The first pouch contains a wipe saturated in a hypochlorite solution, the second pouch contains a wipe saturated in thiosulfate solution, and the third pouch contains a wipe saturated in isopropyl alcohol solution. The deactivation wipe kit may be used in a clean room to deactivate most hazardous drugs on a work surface.
Inventors: Mark J. Compo (Doylestown, Pennsylvania), Michael Balestri (Mechanicsville, Virginia)
Assignee: Veltek Associates (Malvern, Pennsylvania)
Sept. 7, 2021

Data management system and method
Patent No. 1,108,674
Aspects of the present disclosure are directed to electronic computer implemented methods of data communication. The method may include via a computer-based originating data communication network, receiving a smart data payload including an originating node attribute, an injectable tracking attribute and at least one data element associated with a computer readable record; electronically processing the smart data payload including the ID attribute, the injectable tracking attribute and the at least one data element associated; electronically extracting the injectable tracking attribute to determine a network location and electronically transmitting a data element associated with injectable tracking attribute to the originating data communication network for storage in a computer readable database.
Inventors: Kevin A. Delson (Woodland Hills, California), Ronald D. Hooper (Charlotte, North Carolina), Manu Kurian (Dallas, Texas), Megan Kelly (Richmond)
Assignee: Bank of America Corp. (Charlotte, North Carolina)
Aug. 31, 2021

Electrolytes containing superhalogens for metal ion batteries
Patent No. 11,108,087
Compounds (salts) for use as electrolytes, e.g. in batteries such as Li ion, Na ion and Mg ion batteries are provided. The negative ions (anions) of the compounds are complex molecules containing superhalogens, and thus exhibit improved safety, and yet have electron affinities that are equal to or greater than those of halogens. In addition, the binding energy between Li+ and the anions is relatively small so ions can move easily from one electrode to the other in solutions in which the compounds are dissolved. A further advantage is that the affinity of the electrolyte for water is also relatively low so that batteries in which the electrolytes are used have longer lives than those of the prior art.
Inventors: Jena Purusottam (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Aug. 31, 2021

Systems and methods for merging a virtual world, live events and an entertainment channel
Patent No. 11,107,105
Systems, methods and software merge a Virtual World, Live Event and Entertainment Channel, thus creating “The Perfect Storm” of gaming and entertainment whereby the characters of a social network game (e.g., an online fantasy sports league) are represented by human beings who register to be avatars of characters supported by a “Character Service Center,” while players compete to bring avatars to life in a Real World event (e.g., a Real World sports league), where the human beings behind the avatars compete for prizes while staying in character, as these competitors and players are incentivized by a “Collaboration Incentive Platform.”
Inventors: Kenneth Lloyd Tayloe (Los Angeles, California), Paul Howard Glass (Westlake Village, California), David Eugene Williamson Jr. (Richmond), Jordan William Snider (Los Angeles, California)
Assignee: MWE Live (Hermosa Beach, California)
Aug. 31, 2021

Fuzzy search of graph database
Patent No. 11,106,736
A method may compiling, using at least one processor, a corpus of training data by obtaining, for each respective concept object in an ontology, a respective concept label and respective annotations describing the respective concept object; generating a vocabulary of terms based on the corpus of training data; training a semantic model using the corpus of training data and the vocabulary of terms, wherein input features for the semantic model are based on context words in proximity to a term in the vocabulary of terms; and storing a set of word embeddings for the vocabulary of terms based on the trained semantic model.
Inventors: David Newman (Walnut Creek, California), Omar B. Khan (Richmond), Nathan Anthony Susanj (York, Pennsylvania), Alexander Joseph Kalinowski (Philadelphia, Pennsylvania)
Assignee: Wells Fargo Bank (San Francisco, California)

Extruded mat
Patent No. 11,105,099
A drainage component having a continuous, extruded mat having an upper face and a lower face. The mat includes a plurality of patterned three-dimensional structures, each structure spaced from all adjacent structures, and the plurality of patterned three-dimensional structures are provided in a plurality of linear rows or columns in a first direction.
Inventors: Lori C. Hascher (Candler, North Carolina), James E. Mathis (Candler, North Carolina), W. Allan Wingfield (Candler, North Carolina), Wazir Nobbee (Richmond), Rupa Kibbe (Wilmington, Delaware)
Assignee: Low & Bonar (Candler, North Carolina)
E.I. Du Pont de Nemours and Co. (Wilmington, Delaware)
Aug. 31, 2021

Compositions and methods for producing tobacco plants and products having reduced or eliminated suckers
Patent No. 11,104,912
The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
Inventors: Dongmei Xu (Glen Allen, Virginia), Jesse Frederick (Richmond), Chengalrayan Kudithipudi (Midlothian, Virginia), Yanxin Shen (Glen Allen, Virginia), James Strickland (Richmond), Jaemo Yang (Richmond)
Assignee: Altria Client Services (Richmond)
Aug. 31, 2021

Metabolically stable vanillin derivatives for the treatment of hypoxia
Patent No. 11,104,632
Vanillin derivative compounds that bind covalently with hemoglobin are provided. Methods of treating sickle cell disease and other hypoxia-related disorders by administering such compounds are also provided.
Inventors: Abdelsattar Mansour Ebeid Omar (Jeddah, Saudi Arabia), Moustafa El-Sayed El-Araby (Jeddah, Saudi Arabia), Martin K. Safo (Richmond)
Assignee: King Abdulaziz University (Jeddah, Saudi Arabia) & Virginia Commonwealth University (Richmond)
Aug. 31, 2021

Product portion enrobing machines and methods
Patent No. 11,103,002
An apparatus for enrobing a product portion can include at least one polymer spray head adapted to create at least one flow of polymeric fibers to produce at least one polymer enrobing zone and a conveyor system adapted to move at least one product portion from at least one position below at least one polymer enrobing zone and to at least one position above at least one polymer enrobing zone to drop each product portion through one or more polymer enrobing zones a plurality times at different orientations to enrobe each product portion with polymeric fibers.
Inventors: Andrew Nathan Carroll (Chester, Virginia), Shannon Maxwell Black (Richmond), Yan Helen Sun (Midlothian, Virginia), William J. Burke (Nashville, Tennessee), Robert Smith (Glen Allen, Virginia)
Assignee: Altria Client Services (Richmond)
Aug. 31, 2021

Patient identification systems and methods
Patent No. 11,106,818
Systems and methods for managing patient information across various electronic medical record (EMR) systems, according to some examples can involve providing a patient information management system having a cloud-based application server including a database, a client application interface and a mobile security token. A one-time verification code can be sent from the cloud-based application server to the client computing device and read using the mobile security token. The mobile security token can be matched to a patient demographic record in the database to authenticate the patient using the linked mobile security token.
Inventors: David Batchelor (Newcastle, California), Catherine Schulten (Chesterfield, Virginia), Elvar H. Olafsson (Roseville, California)
Assignee: LifeMed ID (Citrus Heights, California)
Aug. 31, 2021

LED sleeve for emergency breathing safety system connection
Patent No. 11,107,341
An air supply indicator apparatus for indicating an amount of breathing air remaining in a cylinder, the apparatus including a housing member having a first side integrally formed with an attachment member, the attachment member configured to be detachably coupled to an emergency breathing safety system (EBSS) or universal emergency breathing safety system (UEBBS) and a second side form with an enclosure, an air status management status indicator having a plurality of indicator light sources disposed on the housing member, and a processor disposed within the enclosure, the processor coupled to the air status management status indicator and configured to emit light from the plurality of indicator light sources based on received signals corresponding to an amount of air remaining in a cylinder.
Inventors: Jamie Little (Midlothian, Virginia)
Assignee: N/A
Aug. 31, 2021

.sup.18F-labeled compounds for PET imaging and uses thereof
Patent No. 11,103,603
The present invention relates to .sup.18F-labeled compounds suitable for positron emission tomography (PET) imaging. The invention further relates to the use of these compounds for carrying out PET scans, imaging the indoleamine 2,3-dioxygenase, pathway, predicting the responsiveness of a subject with a solid tumor to therapies including immunotherapy such as PD-1/PD-L1 inhibition, and determining whether a solid tumor in a subject contains tumor-infiltrating immune cells.
Inventors: Zibo Li (Chapel Hill, North Carolina), Zhanhong Wu (Chapel Hill, North Carolina), Ben Giglio (Henrico, Virginia), Stergios Moschos (Durham, North Carolina)
Assignee: The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
Aug. 31, 2021

Model-based promotion and price computation system and method
Patent No. 11,113,710
A system and method for providing model-based promotion and price computation is described in which promotional offers in the form of promotion information from a manufacturer are combined with price determination parameters from the retailer to calculate a final retail price. The system prevents fraud by eliminating the heavy dependence on unverifiable trust between the retailer and manufacturer and by assuring that the consumer will receive the benefit of the promotions intended by the manufacturer.
Inventors: William R. Sweeney (Richmond)
Assignee: Philip Morris USA (Richmond)
Sept. 7, 2021

Glutamine antagonists for the treatment of cognitive deficits and psychiatric disorders
Patent No. 11,110,104
The disclosure provides compounds having formula (I): ##STR00001## and the pharmaceutically acceptable salts thereof, wherein R.sub.1, R.sub.2, R.sub.2′, and X are as defined as set forth in the specification, for use in treating cognitive deficits and/or psychiatric disorders, such as those associated with neurological or neurodegenerative disorders, psychiatric or mood disorders, and HIV-associated neurocognitive disorders (HAND). Compounds having formula (I) are prodrugs that release glutamine analogs, e.g., 6-diazo-5-oxo-L-norleucine (DON).
Inventors: Barbara Slusher (Kingsville, Maryland), David Volsky (Scarsdale, New York), Mike Nedelcovych (Richmond), Kristen Hollinger (Parkton, Maryland), Atsushi Kamiya (Pikesville, Maryland)
Assignee: The Johns Hopkins University (Baltimore, Maryland) & Icahn School of Medicine at Mount Sinai (New York, New York)
Sept. 7, 2021

Knowledge-based decision support systems and method for process lifecycle automation
Patent No. 11,113,640
Computer implemented knowledge-based decision support system and method is provided. The method includes registering one or more software applications and data sources; defining processes to be implemented by executing the registered one or more software applications; orchestrating execution of the registered one or more software applications for implementing the processes; monitoring system performance based on the execution of the registered one or more software applications; generating analytics data related to the monitored system performance; updating a database with historical data using the generated analytics data; generating an analytical report by analyzing, using a machine learning technique, the historical data stored in the database as well as the generated analytics data; generating automatically user interface based on at least one of a layout and a specification provided by a user; modifying execution of the registered one or more software applications based on the generated analytical report; and displaying data from the generated analytical report using the user interface.
Inventors: Sreedhar Chintalapaty (Frisco, Texas), Seekar Ghodgaonkar (Glen Allen, Virginia), Dhamodararaj Kannan (Round Rock, Texas), Aashish Chandra (Fremont, California)
Assignee: Tata Consultancy Services Limited (Mumbai, India)
Sept. 7, 2021

Deactivation wipe kit
Patent No. 11,111,466
A hazardous drug deactivation wipe kit includes a first pouch having a one-way valve coupled to an end thereof, a second pouch, and a third pouch. The first pouch contains a wipe saturated in a hypochlorite solution, the second pouch contains a wipe saturated in thiosulfate solution, and the third pouch contains a wipe saturated in isopropyl alcohol solution. The deactivation wipe kit may be used in a clean room to deactivate most hazardous drugs on a work surface.
Inventors: Mark J. Compo (Doylestown, Pennsylvania), Michael Balestri (Mechanicsville, Virginia)
Assignee: Veltek Associates (Malvern, Pennsylvania)
Sept. 7, 2021

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