Selective capture and release of analytes
Patent No. 9,250,169
The described subject matter includes techniques and components for minimally invasive, selective capture and release of analytes. An aptamer is selected for its binding affinity with a particular analyte(s). The aptamer is functionalized on a solid phase, for example, microbeads, polymer monolith, microfabricated solid phase, etc. The analyte is allowed to bind to the aptamer, for example, in a microchamber. Once the analyte has been bound, a temperature control sets the temperature to an appropriate temperature at which the captured analyte is released.
Inventors: Jingyue Ju (Englewood Cliffs, N.J.), Donald W. Landry (New York, N.Y.), Qiao Lin (New York, N.Y.), ThaiHuu Nguyen (Richmond), Renjun Pei (Jiangsu, China), Chunmei Oiu (New York, N.Y.), Milan N. Stojanovic (Fort Lee, N.J.)
Assignee: The Trustees Of Columbia University In The City Of New York (New York, N.Y.)
Feb. 2, 2016
Fuel additives for treating internal deposits of fuel injectors
Patent No. 9,249,769
A fuel composition and method for cleaning up internal components of a fuel injector and for improver injector performance for a diesel engine. The composition includes major amount of middle distillate fuel having a sulfur content of 50 ppm by weight or less, and from about 1 to about 30 ppm by weight based on a total weight of fuel of a fuel soluble hydrocarbyl sulfonic acid or salt such as an alkyl aryl sulfonic acid or salt thereof, wherein the alkyl aryl sulfonic acid or salt thereof is effective to improve injector performance.
Inventors: Scott D. Schwab (Richmond), Xinggao Fang (Midlothian, Va.)
Assignee: Afton Chemical Corp. (Richmond)
Feb. 2, 2016
Additive compositions with a friction modifier and a dispersant
Patent No. 9,249,371
A lubricating composition comprising a major amount of base oil and a minor amount of an additive package, wherein the additive package comprises (A) a friction modifier component selected from: (a) one or more a reaction products of an alcohol with a compound of the formula IV: ##STR00001## wherein R is a linear or branched, saturated, unsaturated, or partially saturated hydrocarbyl group having about 8 to about 22 carbon atoms; and (b) one or more compounds of the Formulae II-III: ##STR00002## wherein R is as defined above and R.sub.2 and R.sub.3 are independently selected from hydrogen, C.sub.1-C.sub.18hydrocarbyl groups, and C.sub.1-C.sub.18hydrocarbyl groups containing one or more heteroatoms; and ##STR00003## wherein R is as defined above; and X is an alkali metal, alkaline earth metal or ammonium cation and n is the valence of cation X; and (B) at least one dispersant.
Inventors: John T. Loper (Richmond), Jeremy P. Styer (Richmond)
Assignee: Afton Chemical Corp. (Richmond)
Feb. 2, 2016
OMPA and ASP14 in vaccine compositions and as diagnostic targets
Patent No. 9,248,174
Anaplasma phagocytophilum surface proteins Asp14 and OmpA and homologous genes from Anaplasmatacaea family members are used in compositions suitable for vaccines to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. Asp14 and/or OmpA proteins or peptide fragments may be used in combination with other Anaplasmatacaea surface proteins to elicit an immune response. Furthermore, antibodies to Asp14 and/or OmpA proteins can be used in diagnostic methods to determine whether an individual has contracted an Anaplasmatacaea infection. Because of the conserved invasin domains in the surface proteins, a wide range of Anaplasmatacaea infections may be diagnosed, treated or prevented using compositions of the invention.
Inventors: Jason A. Carlyon (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Feb. 2, 2016
In situ formation of catalytic cigarette paper
Patent No. 9,255,361
Methods for the in situ formation of catalyst particles in cigarette paper are provided. A catalyst precursor, which can be incorporated into the cigarette papermaking process or can be combined with cigarette paper after formation of the paper, can be decomposed to form catalyst particles that are incorporated within the cigarette paper. Cigarette paper comprising the catalyst particles can be used to form a cigarette. During the smoking of a cigarette comprising the catalyst particles the amount of carbon monoxide in the mainstream smoke of the cigarette can be reduced.
Inventors: Shalva Gedevanishvili (Richmond), Shahryar Rabiei (Richmond)
Assignee: Philip Morris Usa Inc. (Richmond)
Feb. 9, 2016
Biological-chemical treatment of liquid organic wastewater
Patent No. 9,255,022
The invention is directed to systems and methods of biological and chemical treatment of wastewater comprising organic nitrogen compounds. Systems may include: an aerobic reactor, a first separation module for separating liquid and solid components of the wastewater; an oxidation module for removing organic materials from the wastewater; and a post-anoxic reactor for denitrifying at least a portion of the wastewater. Systems may include a second separation module and various feedback recycle lines between the components. Methods may include: degrading by the aerobic reactor more than 95% of organic compounds to ammonia, oxidizing by the oxidation module at least a portion of the ammonia to nitrates, and degrading by the post-anoxic reactor at least a portion of the nitrates to nitrogen gas and water. Systems and methods may reduce total organic carbon of the wastewater by more than 90%, and total nitrogen of the wastewater by more than 90%.
Inventors: Sunil Mehta (Henrico, Va.), Nabin Chowdhury (Glen Allen, Va.), Richard Ubaldi (Glen Allen, Va.), Barbara Schilling (West Orange, N.J.), Antonio Lau (Richmond), Bruno Heiniger (Boll, Switzerland)
Assignee: Infilco Degremont Inc (Richmond)
Feb. 9, 2016
Suspended play structure
Patent No. 9,254,446
A suspended play structure includes a floor, a sidewall, and a roof that defines an inner space. The structure includes top and bottom ring structures that provide additional support to the play structure. The play structure can be suspended from a tree, a stand, a ceiling, or similar structure. The structure is collapsible for easy storage and can also include a removable cushion that can fit within an internal pocket. The structure can also include a removable string of LED lights within the inner space.
Inventors: Amanda T. Lacy (Charlottesville, Va.), Beverly Fries (Barboursville, Va.), Ting Xu (Richmond)
Assignee: Plow & Hearth, LLC (Madison, Va.)
Feb. 9, 2016
Systems and methods to monitor pump cavitation
Patent No. 9,255,578
Systems and methods to monitor pump cavitation are disclosed. An example method includes monitoring a pressure parameter and a vibration parameter associated with an asset in an operating process unit. The example method includes calculating a manipulated pressure value based on the pressure parameter. The example method includes calculating a manipulated vibration value based on the vibration parameter. The example method includes determining a state of cavitation associated with the asset based on at least one of the manipulated pressure value or the manipulated vibration value.
Inventors: Joseph H. Sharpe Jr. (Glen Allen, Va.), Gary Hawkins (Clarendon Hills, Ill.), Robert Skeirik (Knoxville, Tenn.)
Assignee: Fisher-Rosemount Systems Inc. (Round Rock, Texas)
Feb. 9, 2016
Reagent injection system for exhaust of turbine system
Patent No. 9,255,507
A reagent injection system for a catalytic emissions reduction assembly of a combustion turbine that includes an exhaust duct and at least one injector. The exhaust duct includes a first section including an entrance end and an exit end, wherein the entrance end is configured to be fluidly coupled to the combustion turbine to receive exhaust gases therefrom. The exhaust duct also includes and a second section having an entrance end that is fluidly coupled to the exit end of the first section. The at least one injector is operatively coupled to one of the first and second sections, and each injector is configured to inject a reagent into the exhaust gases flowing through the exhaust duct.
Inventors: Mark A. Forwerck (Marvin, N.C.), Lawrence J. Muzio (Laguna Niguel, Calif.), Matthew Zedler (Midlothian, Va.)
Assignee: LP Amina LLC (Charlotte, N.C.)
Feb. 9, 2016
Selective capture and release of analytes
Patent No. 9,250,169
The described subject matter includes techniques and components for minimally invasive, selective capture and release of analytes. An aptamer is selected for its binding affinity with a particular analyte(s). The aptamer is functionalized on a solid phase, for example, microbeads, polymer monolith, microfabricated solid phase, etc. The analyte is allowed to bind to the aptamer, for example, in a microchamber. Once the analyte has been bound, a temperature control sets the temperature to an appropriate temperature at which the captured analyte is released.
Inventors: Jingyue Ju (Englewood Cliffs, N.J.), Donald W. Landry (New York, N.Y.), Qiao Lin (New York, N.Y.), ThaiHuu Nguyen (Richmond), Renjun Pei (Jiangsu, China), Chunmei Oiu (New York, N.Y.), Milan N. Stojanovic (Fort Lee, N.J.)
Assignee: The Trustees Of Columbia University In The City Of New York (New York, N.Y.)
Feb. 2, 2016
Fuel additives for treating internal deposits of fuel injectors
Patent No. 9,249,769
A fuel composition and method for cleaning up internal components of a fuel injector and for improver injector performance for a diesel engine. The composition includes major amount of middle distillate fuel having a sulfur content of 50 ppm by weight or less, and from about 1 to about 30 ppm by weight based on a total weight of fuel of a fuel soluble hydrocarbyl sulfonic acid or salt such as an alkyl aryl sulfonic acid or salt thereof, wherein the alkyl aryl sulfonic acid or salt thereof is effective to improve injector performance.
Inventors: Scott D. Schwab (Richmond), Xinggao Fang (Midlothian, Va.)
Assignee: Afton Chemical Corp. (Richmond)
Feb. 2, 2016
Additive compositions with a friction modifier and a dispersant
Patent No. 9,249,371
A lubricating composition comprising a major amount of base oil and a minor amount of an additive package, wherein the additive package comprises (A) a friction modifier component selected from: (a) one or more a reaction products of an alcohol with a compound of the formula IV: ##STR00001## wherein R is a linear or branched, saturated, unsaturated, or partially saturated hydrocarbyl group having about 8 to about 22 carbon atoms; and (b) one or more compounds of the Formulae II-III: ##STR00002## wherein R is as defined above and R.sub.2 and R.sub.3 are independently selected from hydrogen, C.sub.1-C.sub.18hydrocarbyl groups, and C.sub.1-C.sub.18hydrocarbyl groups containing one or more heteroatoms; and ##STR00003## wherein R is as defined above; and X is an alkali metal, alkaline earth metal or ammonium cation and n is the valence of cation X; and (B) at least one dispersant.
Inventors: John T. Loper (Richmond), Jeremy P. Styer (Richmond)
Assignee: Afton Chemical Corp. (Richmond)
Feb. 2, 2016
OMPA and ASP14 in vaccine compositions and as diagnostic targets
Patent No. 9,248,174
Anaplasma phagocytophilum surface proteins Asp14 and OmpA and homologous genes from Anaplasmatacaea family members are used in compositions suitable for vaccines to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. Asp14 and/or OmpA proteins or peptide fragments may be used in combination with other Anaplasmatacaea surface proteins to elicit an immune response. Furthermore, antibodies to Asp14 and/or OmpA proteins can be used in diagnostic methods to determine whether an individual has contracted an Anaplasmatacaea infection. Because of the conserved invasin domains in the surface proteins, a wide range of Anaplasmatacaea infections may be diagnosed, treated or prevented using compositions of the invention.
Inventors: Jason A. Carlyon (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Feb. 2, 2016
In situ formation of catalytic cigarette paper
Patent No. 9,255,361
Methods for the in situ formation of catalyst particles in cigarette paper are provided. A catalyst precursor, which can be incorporated into the cigarette papermaking process or can be combined with cigarette paper after formation of the paper, can be decomposed to form catalyst particles that are incorporated within the cigarette paper. Cigarette paper comprising the catalyst particles can be used to form a cigarette. During the smoking of a cigarette comprising the catalyst particles the amount of carbon monoxide in the mainstream smoke of the cigarette can be reduced.
Inventors: Shalva Gedevanishvili (Richmond), Shahryar Rabiei (Richmond)
Assignee: Philip Morris Usa Inc. (Richmond)
Feb. 9, 2016
Biological-chemical treatment of liquid organic wastewater
Patent No. 9,255,022
The invention is directed to systems and methods of biological and chemical treatment of wastewater comprising organic nitrogen compounds. Systems may include: an aerobic reactor, a first separation module for separating liquid and solid components of the wastewater; an oxidation module for removing organic materials from the wastewater; and a post-anoxic reactor for denitrifying at least a portion of the wastewater. Systems may include a second separation module and various feedback recycle lines between the components. Methods may include: degrading by the aerobic reactor more than 95% of organic compounds to ammonia, oxidizing by the oxidation module at least a portion of the ammonia to nitrates, and degrading by the post-anoxic reactor at least a portion of the nitrates to nitrogen gas and water. Systems and methods may reduce total organic carbon of the wastewater by more than 90%, and total nitrogen of the wastewater by more than 90%.
Inventors: Sunil Mehta (Henrico, Va.), Nabin Chowdhury (Glen Allen, Va.), Richard Ubaldi (Glen Allen, Va.), Barbara Schilling (West Orange, N.J.), Antonio Lau (Richmond), Bruno Heiniger (Boll, Switzerland)
Assignee: Infilco Degremont Inc (Richmond)
Feb. 9, 2016
Suspended play structure
Patent No. 9,254,446
A suspended play structure includes a floor, a sidewall, and a roof that defines an inner space. The structure includes top and bottom ring structures that provide additional support to the play structure. The play structure can be suspended from a tree, a stand, a ceiling, or similar structure. The structure is collapsible for easy storage and can also include a removable cushion that can fit within an internal pocket. The structure can also include a removable string of LED lights within the inner space.
Inventors: Amanda T. Lacy (Charlottesville, Va.), Beverly Fries (Barboursville, Va.), Ting Xu (Richmond)
Assignee: Plow & Hearth, LLC (Madison, Va.)
Feb. 9, 2016
Systems and methods to monitor pump cavitation
Patent No. 9,255,578
Systems and methods to monitor pump cavitation are disclosed. An example method includes monitoring a pressure parameter and a vibration parameter associated with an asset in an operating process unit. The example method includes calculating a manipulated pressure value based on the pressure parameter. The example method includes calculating a manipulated vibration value based on the vibration parameter. The example method includes determining a state of cavitation associated with the asset based on at least one of the manipulated pressure value or the manipulated vibration value.
Inventors: Joseph H. Sharpe Jr. (Glen Allen, Va.), Gary Hawkins (Clarendon Hills, Ill.), Robert Skeirik (Knoxville, Tenn.)
Assignee: Fisher-Rosemount Systems Inc. (Round Rock, Texas)
Feb. 9, 2016
Reagent injection system for exhaust of turbine system
Patent No. 9,255,507
A reagent injection system for a catalytic emissions reduction assembly of a combustion turbine that includes an exhaust duct and at least one injector. The exhaust duct includes a first section including an entrance end and an exit end, wherein the entrance end is configured to be fluidly coupled to the combustion turbine to receive exhaust gases therefrom. The exhaust duct also includes and a second section having an entrance end that is fluidly coupled to the exit end of the first section. The at least one injector is operatively coupled to one of the first and second sections, and each injector is configured to inject a reagent into the exhaust gases flowing through the exhaust duct.
Inventors: Mark A. Forwerck (Marvin, N.C.), Lawrence J. Muzio (Laguna Niguel, Calif.), Matthew Zedler (Midlothian, Va.)
Assignee: LP Amina LLC (Charlotte, N.C.)
Feb. 9, 2016