Ultra-small ApoB-containing particles and methods of use thereof
Patent No. 9,322,833
The present disclosure provides an isolated particle comprising very high density, ultra small, lipid depleted apo B containing particles, and may also contain cytokeratin 8. The isolated particle is useful in diagnostic assays, which are also provided.
Inventors: Ronald M. Krauss (Berkeley, Calif.), Mohmed Elfatih Ashmaig (Richmond)
Assignee: Children’s Hospital & Research Center at Oakland (Oakland, Calif.)
April 26, 2016
Hydroxyalkyl substituted succinimides and fuels containing them
Patent No. 9,321,976
A fuel composition and method for reducing friction or wear and improving fuel economy in an engine. The fuel composition includes gasoline and from about 10 to about 750 ppm by weight based on a total weight of the fuel composition of a hydroxyalkyl hydrocarbyl-substituted succinimide compound having at least two hydroxyl groups attached to a tertiary nitrogen atom of a polyamino group through a hydrocarbyl link, wherein the hydroxyalkyl hydrocarbyl-substituted succinimide is devoid of primary and secondary amino groups.
Inventors: Xinggao Fang (Midlothian, Va.), Scott A. Culley (Midlothian, Va.), Scott D. Schwab (Richmond)
Assignee: Afton Chemical Corp. (Richmond)
April 26, 2016
Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
Patent No. 9,321,802
The sulfated oxysterol 5-cholesten-3.beta., 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided.
Inventors: Shunlin Ren (Richmond), William M. Pandak (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
April 26, 2016
Product dispensing system with sound reducing features
Patent No. 9,320,365
A product dispensing system having a frame with a front end and a rear end, and including an upper support deck extending between the front end and the rear end, a lower support deck positioned below the upper support deck, the lower support deck extending between the front end and the rear end and defining a product display area, a guide extending from proximate the upper support deck to proximate the lower support deck, and a stop positioned proximate the product display area.
Inventors: James Fortuna (Richmond), Caleb Loftin (Richmond), Joseph Snead (Chesterfield, Va.)
Assignee: WestRock MWV (Norcross, Ga.)
April 26, 2016
Management of energy demand and energy efficiency savings from voltage optimization on electric power systems using AMI-based data analysis
Patent No. 9,325,174
A method, apparatus, system and computer program is provided for controlling an electric power system, including implementation of a voltage control and conservation (VCC) system used to optimally control the independent voltage and capacitor banks using a linear optimization methodology to minimize the losses in the EEDCS and the EUS. An energy validation process system (EVP) is provided which is used to document the savings of the VCC and an EPP is used to optimize improvements to the EEDCS for continuously improving the energy losses in the EEDS. The EVP system measures the improvement in the EEDS a result of operating the VCC system in the “ON” state determining the level of energy conservation achieved by the VCC system.
Inventors: Stephen J. Tyler (Henrico County, Va.), Phillip W. Powell (Chesterfield, Va.)
Assignee: Dominion Resources Inc. (Richmond)
April 26, 2016
Tobacco nicotine demethylase genomic clone and uses thereof
Patent No. 9,322,030
The present invention features tobacco nicotine demethylase nucleic acid and amino acid sequences, tobacco plants and plant components containing such sequences, including tobacco plants and plant components having reduced expression or altered enzymatic activity of nicotine demethylase, methods of use of nicotine demethylase sequences to create plants having altered levels of nornicotine or N’-nitrosonornicotine (“NNN”) or both relative to a control plant, as well as tobacco articles having reduced levels of nornicotine or NNN.
Inventors: Dongmei Xu (Glen Allen, Va.)
Assignee: U.S. Smokeless Tobacco Co. (Richmond)
April 26, 2016
Building control system
Patent No. 9,325,573
A method of operating a building control system includes installing a plurality of network devices to a communications network. Each of the plurality of network devices performs a device operation. The method also includes assigning an identifier to each of the plurality of network devices. The identifier is based on the device operation and a device location. The method further includes communicating information and coordinating operations automatically among the plurality of network devices based on the identifier.
Inventors: Michael Johnson Swainston (Mechanicsville, Va.)
Assignee: Schneider Electric Buildings AB (Malmo, Sweden)
April 26, 2016
Mobile UVA curing system for collision and cosmetic repair of automobiles
Patent No. 9,324,467
A mobile radiation system is provided. The mobile radiation system comprises a mobile radiation device coupled to a control unit; a radiation blocker having an adaptor opening for receiving said mobile radiation device when said mobile radiation device is in a seated position on said radiation blocker; and a mobile carrier comprising a first compartment for housing said radiation blocker, a second compartment for housing said control unit, and a carrier motion device. The adaptor opening can dimensionally fit the mobile radiation device to block radiations from the mobile radiation device when said mobile radiation device is in the seated position. The mobile radiation device can produce radiation having peak radiation wavelength in a range of from about 250 nm to about 450 nm and can have a peak irradiation power in a range of from about 0.5 W/cm.sup.2 to about 10 W/cm.sup.2.
Inventors: John Wilson (Delray Beach, Fla.), John Larson (West Chester, Penn.) Andrew Seyler (Henrico, Va.)
Assignee: Axalta Coating Systems IP Co. (Wilmington, Del.)
April 26, 2016
Network traffic monitoring
Patent No. 9,331,907
A first set of bandwidth utilization data comprising a bandwidth utilization for one or more links in a network is determined. Also, a second set of bandwidth utilization data comprising a bandwidth utilization for one or more media paths in the network is determined. At least some of the first set of bandwidth utilization data is compared to at least some of the second set of bandwidth utilization data, thereby providing information useful for monitoring the network.
Inventors: Peter J. Gerstenberger (Arlington, Va.), Jessica Salomonsky (Richmond)
Assignee: Verizon Patent and Licensing Inc. (Basking Ridge, N.J.)
May 3, 2016
Assay wick with analyte fluid sufficiency indicator
Patent No. 9,330,580
A wick for use in determining sufficiency of an amount of analyte fluid provided to an analyte test section of an assay device is provided. The wick comprises a primary wick portion attached or attachable to the analyte test section so as to be in fluid communication therewith. The primary wick portion has a receiving surface adapted for receiving the analyte fluid and is configured to draw the analyte fluid from a first area to a second area of the primary wick portion. The assay wick further comprises an indicator portion having a contrasting visual characteristic. The indicator surface is covered by at least a portion of the primary wick portion, which comprises a wicking material that becomes more light transmissive when wetted by the analyte fluid. The contrasting visual characteristic is viewable through the at least a portion of the primary wick portion only when the at least a portion of the primary wick portion is suffused by the analyte fluid.
Inventors: Bennett C. Ward (Midlothian, Va.), Jian Xiang (Midlothian, Va.), Stacey L. Tibbs (Colonial Heights, Va.), Yelena N. Rogova (Richmond)
Assignee: Essentra Porous Technologies Corp. (Colonial Heights, Va.)
May 3, 2016
Medical injector with compliance tracking and monitoring
Patent No. 9,327,077
A system includes a medicament delivery device and a container configured to receive at least a portion of the medicament delivery device. The medicament delivery device includes an actuator and a first electronic circuit system. The actuator is configured to initiate delivery of a medicament into a body when the actuator is moved from a first position to a second position. The first electronic circuit system is configured to output a first electronic signal when the actuator is moved from the first position to the second position. The container includes a second electronic circuit system configured to receive the first electronic signal. The second electronic circuit system is configured to output a second electronic signal associated with the first electronic signal.
Inventors: Eric S. Edwards (Midlothian, Va.), Evan T. Edwards (Fredericksburg, Va.), Mark J. Licata (Doswell, Va.), Paul F. Meyers (Fishers, Ind.), David A. Weinzierl (Andover, Minn.), T. Spencer Williamson IV (Richmond)
Assignee: kaleo Inc. (Richmond)
May 3, 2016
System and method for mitigating the effects of tissue blood volume changes to aid in diagnosing infiltration or extravasation in animalia tissue
Patent No. 9,326,686
A system including a sensor and a device coupled to the sensor. The sensor is configured to detect in Animalia tissue (i) a first electromagnetic radiation extinction dominated by absorption of a first wavelength and (ii) a second electromagnetic radiation extinction dominated by scattering of a second wavelength. The device is configured to aid in diagnosing at least one of infiltration and extravasation in the Animalia tissue based on the first and second electromagnetic radiation extinctions detected by the sensor.
Inventors: Gary P. Warren (Williamsburg, Va.), Matthew S. Alley (Sandston, Va.), Scott J. Anchell (Fairfax Station, Va.), Javier A. Garriz (Hampton, Va.), William J. Naramore (Richmond), Garret T. Bonnema (Williamsburg, Va.)
Assignee: ivWatch (Hampton, Va.)
May 3, 2016
Botanical antioxidant compositions and methods of preparation and use thereof
Patent No. 9,326,932
A botanical antioxidant composition includes a botanical antioxidant extract blend including a first antioxidant botanical extract including at least one hydroxycinnamic acid, and at least one additional antioxidant botanical extracts including at least one antioxidant selected from the group consisting of vitamins, stilbenoids, curcumininoids, tannins, flavones, flavonols, flavan-3-ols, flavanones, anthocyanidins, anthocyanins, isoflavones, flavanonols, proanthocyanidins, dihydroxybenzoic acids, and pyridine alkaloids.
Inventors: Joseph Abernathy Lewis II (Chesterfield, Va.), Joseph C. Dinardo (Vesuvius, Va.)
Assignee: US Cosmeceutechs (Richmond, Va.)
May 3, 2016
Electronic vaping article
Patent No. 9,326,547
An electronic smoking article includes an outer tube extending in a longitudinal direction, an inner tube within the outer tube and including a pair of opposing slots, a liquid supply comprising a liquid material, a coil heater, a wick and a mouth end insert. The coil heater is located in the inner tube. The coil heater is formed of an iron-free, nickel-chromium alloy and has substantially uniformly spaced windings. The wick is surrounded by the coil heater such that the wick delivers liquid material to the coil heater and the coil heater heats the liquid material to a temperature sufficient to vaporize the liquid material and form an aerosol in the inner tube.
Inventors: Christopher S. Tucker (Midlothian, Va.), Geoffrey Brandon Jordan (Midlothian, Va.), Barry S. Smith (Hopewell, Va.), Ali A. Rostami (Glen Allen, Va.), Michael J. Mullins (Chesterfield, Va.)
Assignee: Altria Client Services (Richmond, Va.)
May 3, 2016
Method and apparatus for improving heat transfer in industrial water systems with ferrofluids
Patent No. 9,328,276
Disclosed are methods and apparatus for improving heat transfer of recirculating fluids within a system by introducing a ferrofluid in which iron oxide nanoparticles are suspended in a carrier fluid that is, in turn, added to a working fluid for increasing the heat capacity of the working fluid. The ferrofluid suspension can be prepared ex-situ and metered into the working fluid from a separate reservoir or may be prepared in-situ as needed through the use of an inline reactor. The ferrofluid can be introduced with other water treatment additives which are compatible with the colloidal suspension and monitored directly and/or indirectly for controlling the heat capacity performance of the system.
Inventors: John Richardson (Hanover, Va.), Dale P. Stuart (Mechanicsville, Va.), Everett Carpenter (Mechanicsville, Va.)
Assignee: Chemtreat Inc. (Glen Allen, Va.)
May 3, 2016
Ultra-small ApoB-containing particles and methods of use thereof
Patent No. 9,322,833
The present disclosure provides an isolated particle comprising very high density, ultra small, lipid depleted apo B containing particles, and may also contain cytokeratin 8. The isolated particle is useful in diagnostic assays, which are also provided.
Inventors: Ronald M. Krauss (Berkeley, Calif.), Mohmed Elfatih Ashmaig (Richmond)
Assignee: Children’s Hospital & Research Center at Oakland (Oakland, Calif.)
April 26, 2016
Hydroxyalkyl substituted succinimides and fuels containing them
Patent No. 9,321,976
A fuel composition and method for reducing friction or wear and improving fuel economy in an engine. The fuel composition includes gasoline and from about 10 to about 750 ppm by weight based on a total weight of the fuel composition of a hydroxyalkyl hydrocarbyl-substituted succinimide compound having at least two hydroxyl groups attached to a tertiary nitrogen atom of a polyamino group through a hydrocarbyl link, wherein the hydroxyalkyl hydrocarbyl-substituted succinimide is devoid of primary and secondary amino groups.
Inventors: Xinggao Fang (Midlothian, Va.), Scott A. Culley (Midlothian, Va.), Scott D. Schwab (Richmond)
Assignee: Afton Chemical Corp. (Richmond)
April 26, 2016
Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
Patent No. 9,321,802
The sulfated oxysterol 5-cholesten-3.beta., 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided.
Inventors: Shunlin Ren (Richmond), William M. Pandak (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
April 26, 2016
Product dispensing system with sound reducing features
Patent No. 9,320,365
A product dispensing system having a frame with a front end and a rear end, and including an upper support deck extending between the front end and the rear end, a lower support deck positioned below the upper support deck, the lower support deck extending between the front end and the rear end and defining a product display area, a guide extending from proximate the upper support deck to proximate the lower support deck, and a stop positioned proximate the product display area.
Inventors: James Fortuna (Richmond), Caleb Loftin (Richmond), Joseph Snead (Chesterfield, Va.)
Assignee: WestRock MWV (Norcross, Ga.)
April 26, 2016
Management of energy demand and energy efficiency savings from voltage optimization on electric power systems using AMI-based data analysis
Patent No. 9,325,174
A method, apparatus, system and computer program is provided for controlling an electric power system, including implementation of a voltage control and conservation (VCC) system used to optimally control the independent voltage and capacitor banks using a linear optimization methodology to minimize the losses in the EEDCS and the EUS. An energy validation process system (EVP) is provided which is used to document the savings of the VCC and an EPP is used to optimize improvements to the EEDCS for continuously improving the energy losses in the EEDS. The EVP system measures the improvement in the EEDS a result of operating the VCC system in the “ON” state determining the level of energy conservation achieved by the VCC system.
Inventors: Stephen J. Tyler (Henrico County, Va.), Phillip W. Powell (Chesterfield, Va.)
Assignee: Dominion Resources Inc. (Richmond)
April 26, 2016
Tobacco nicotine demethylase genomic clone and uses thereof
Patent No. 9,322,030
The present invention features tobacco nicotine demethylase nucleic acid and amino acid sequences, tobacco plants and plant components containing such sequences, including tobacco plants and plant components having reduced expression or altered enzymatic activity of nicotine demethylase, methods of use of nicotine demethylase sequences to create plants having altered levels of nornicotine or N’-nitrosonornicotine (“NNN”) or both relative to a control plant, as well as tobacco articles having reduced levels of nornicotine or NNN.
Inventors: Dongmei Xu (Glen Allen, Va.)
Assignee: U.S. Smokeless Tobacco Co. (Richmond)
April 26, 2016
Building control system
Patent No. 9,325,573
A method of operating a building control system includes installing a plurality of network devices to a communications network. Each of the plurality of network devices performs a device operation. The method also includes assigning an identifier to each of the plurality of network devices. The identifier is based on the device operation and a device location. The method further includes communicating information and coordinating operations automatically among the plurality of network devices based on the identifier.
Inventors: Michael Johnson Swainston (Mechanicsville, Va.)
Assignee: Schneider Electric Buildings AB (Malmo, Sweden)
April 26, 2016
Mobile UVA curing system for collision and cosmetic repair of automobiles
Patent No. 9,324,467
A mobile radiation system is provided. The mobile radiation system comprises a mobile radiation device coupled to a control unit; a radiation blocker having an adaptor opening for receiving said mobile radiation device when said mobile radiation device is in a seated position on said radiation blocker; and a mobile carrier comprising a first compartment for housing said radiation blocker, a second compartment for housing said control unit, and a carrier motion device. The adaptor opening can dimensionally fit the mobile radiation device to block radiations from the mobile radiation device when said mobile radiation device is in the seated position. The mobile radiation device can produce radiation having peak radiation wavelength in a range of from about 250 nm to about 450 nm and can have a peak irradiation power in a range of from about 0.5 W/cm.sup.2 to about 10 W/cm.sup.2.
Inventors: John Wilson (Delray Beach, Fla.), John Larson (West Chester, Penn.) Andrew Seyler (Henrico, Va.)
Assignee: Axalta Coating Systems IP Co. (Wilmington, Del.)
April 26, 2016
Network traffic monitoring
Patent No. 9,331,907
A first set of bandwidth utilization data comprising a bandwidth utilization for one or more links in a network is determined. Also, a second set of bandwidth utilization data comprising a bandwidth utilization for one or more media paths in the network is determined. At least some of the first set of bandwidth utilization data is compared to at least some of the second set of bandwidth utilization data, thereby providing information useful for monitoring the network.
Inventors: Peter J. Gerstenberger (Arlington, Va.), Jessica Salomonsky (Richmond)
Assignee: Verizon Patent and Licensing Inc. (Basking Ridge, N.J.)
May 3, 2016
Assay wick with analyte fluid sufficiency indicator
Patent No. 9,330,580
A wick for use in determining sufficiency of an amount of analyte fluid provided to an analyte test section of an assay device is provided. The wick comprises a primary wick portion attached or attachable to the analyte test section so as to be in fluid communication therewith. The primary wick portion has a receiving surface adapted for receiving the analyte fluid and is configured to draw the analyte fluid from a first area to a second area of the primary wick portion. The assay wick further comprises an indicator portion having a contrasting visual characteristic. The indicator surface is covered by at least a portion of the primary wick portion, which comprises a wicking material that becomes more light transmissive when wetted by the analyte fluid. The contrasting visual characteristic is viewable through the at least a portion of the primary wick portion only when the at least a portion of the primary wick portion is suffused by the analyte fluid.
Inventors: Bennett C. Ward (Midlothian, Va.), Jian Xiang (Midlothian, Va.), Stacey L. Tibbs (Colonial Heights, Va.), Yelena N. Rogova (Richmond)
Assignee: Essentra Porous Technologies Corp. (Colonial Heights, Va.)
May 3, 2016
Medical injector with compliance tracking and monitoring
Patent No. 9,327,077
A system includes a medicament delivery device and a container configured to receive at least a portion of the medicament delivery device. The medicament delivery device includes an actuator and a first electronic circuit system. The actuator is configured to initiate delivery of a medicament into a body when the actuator is moved from a first position to a second position. The first electronic circuit system is configured to output a first electronic signal when the actuator is moved from the first position to the second position. The container includes a second electronic circuit system configured to receive the first electronic signal. The second electronic circuit system is configured to output a second electronic signal associated with the first electronic signal.
Inventors: Eric S. Edwards (Midlothian, Va.), Evan T. Edwards (Fredericksburg, Va.), Mark J. Licata (Doswell, Va.), Paul F. Meyers (Fishers, Ind.), David A. Weinzierl (Andover, Minn.), T. Spencer Williamson IV (Richmond)
Assignee: kaleo Inc. (Richmond)
May 3, 2016
System and method for mitigating the effects of tissue blood volume changes to aid in diagnosing infiltration or extravasation in animalia tissue
Patent No. 9,326,686
A system including a sensor and a device coupled to the sensor. The sensor is configured to detect in Animalia tissue (i) a first electromagnetic radiation extinction dominated by absorption of a first wavelength and (ii) a second electromagnetic radiation extinction dominated by scattering of a second wavelength. The device is configured to aid in diagnosing at least one of infiltration and extravasation in the Animalia tissue based on the first and second electromagnetic radiation extinctions detected by the sensor.
Inventors: Gary P. Warren (Williamsburg, Va.), Matthew S. Alley (Sandston, Va.), Scott J. Anchell (Fairfax Station, Va.), Javier A. Garriz (Hampton, Va.), William J. Naramore (Richmond), Garret T. Bonnema (Williamsburg, Va.)
Assignee: ivWatch (Hampton, Va.)
May 3, 2016
Botanical antioxidant compositions and methods of preparation and use thereof
Patent No. 9,326,932
A botanical antioxidant composition includes a botanical antioxidant extract blend including a first antioxidant botanical extract including at least one hydroxycinnamic acid, and at least one additional antioxidant botanical extracts including at least one antioxidant selected from the group consisting of vitamins, stilbenoids, curcumininoids, tannins, flavones, flavonols, flavan-3-ols, flavanones, anthocyanidins, anthocyanins, isoflavones, flavanonols, proanthocyanidins, dihydroxybenzoic acids, and pyridine alkaloids.
Inventors: Joseph Abernathy Lewis II (Chesterfield, Va.), Joseph C. Dinardo (Vesuvius, Va.)
Assignee: US Cosmeceutechs (Richmond, Va.)
May 3, 2016
Electronic vaping article
Patent No. 9,326,547
An electronic smoking article includes an outer tube extending in a longitudinal direction, an inner tube within the outer tube and including a pair of opposing slots, a liquid supply comprising a liquid material, a coil heater, a wick and a mouth end insert. The coil heater is located in the inner tube. The coil heater is formed of an iron-free, nickel-chromium alloy and has substantially uniformly spaced windings. The wick is surrounded by the coil heater such that the wick delivers liquid material to the coil heater and the coil heater heats the liquid material to a temperature sufficient to vaporize the liquid material and form an aerosol in the inner tube.
Inventors: Christopher S. Tucker (Midlothian, Va.), Geoffrey Brandon Jordan (Midlothian, Va.), Barry S. Smith (Hopewell, Va.), Ali A. Rostami (Glen Allen, Va.), Michael J. Mullins (Chesterfield, Va.)
Assignee: Altria Client Services (Richmond, Va.)
May 3, 2016
Method and apparatus for improving heat transfer in industrial water systems with ferrofluids
Patent No. 9,328,276
Disclosed are methods and apparatus for improving heat transfer of recirculating fluids within a system by introducing a ferrofluid in which iron oxide nanoparticles are suspended in a carrier fluid that is, in turn, added to a working fluid for increasing the heat capacity of the working fluid. The ferrofluid suspension can be prepared ex-situ and metered into the working fluid from a separate reservoir or may be prepared in-situ as needed through the use of an inline reactor. The ferrofluid can be introduced with other water treatment additives which are compatible with the colloidal suspension and monitored directly and/or indirectly for controlling the heat capacity performance of the system.
Inventors: John Richardson (Hanover, Va.), Dale P. Stuart (Mechanicsville, Va.), Everett Carpenter (Mechanicsville, Va.)
Assignee: Chemtreat Inc. (Glen Allen, Va.)
May 3, 2016