The R&D Dept.: Local patents for 11.1.17

Unnatural reactive amino acid genetic code additions

Patent No. 9,797,908

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Inventors: Alexander Deiters (La Jolla, Calif.), T. Ashton Cropp (Richmond), Jason W. Chin (Cambridge, Great Britain),  J. Christopher Anderson (San Francisco, Calif.), Peter G. Schultz (La Jolla, Calif.)

Assignee:  The Scripps Research Institute (La Jolla, Calif.)

Oct. 24, 2017

Intimate blends of carbon-containing and dyeable fibers

Patent No. 9,797,070

An intimate blend of staple fibers, and a yarn, fabric, and article of clothing providing surprising arc performance and coloration capability, comprising a mixture of a first staple fiber made from a flame resistant polymer that retains at least 90 percent of its weight when heated to 425 degrees Celsius at a rate of 10 degrees per minute and comprises 0.5 to 20 weight percent discrete homogeneously dispersed carbon particles; and either (a) a second staple fiber from a flame resistant polymer being free of discrete carbon particles and having an L* lightness coordinate of 70 or greater and being capable of accepting a dye or coloration, or (b) a second staple fiber blend being free of discrete carbon particles and comprising at least one second staple fiber from a flame resistant polymer and having an L* lightness coordinate of 70 or greater and being capable of accepting a dye or coloration; the mixture having a total content of 0.5 to 3 weight percent discrete carbon particles.

Inventors:  Christopher William Newton (Richmond), Reiyao Zhu (Moseley, Va.)

Assignee:  E I Du Pont De Nemours and Co. (Wilmington, Del.)

Oct. 24, 2017

Compositions comprising C5 and C6 oligosaccharides

Patent No. 9,797,021

Compositions comprising C5 and C6 saccharides of varying degrees of polymerization and low levels of undesirable impurities, such as compounds containing sulfur, nitrogen, or metals, are disclosed.

Inventors:  Daniel Clay Floyd (Richmond), Kiran Kadam (Golden, Colo.), Srinivas Kilambi (Duluth, Ga.)

Assignee:  Renmatix Inc. (King of Prussia, Pa.)

Oct. 24, 2017

Kitchen appliance for preparing a beverage and method of operating same

Patent No. 9,795,245

A kitchen appliance includes a first reservoir for receiving a liquid to be used for preparing a beverage and a hot water generator (`HWG`) which has an inlet end, an outlet end and a passageway there between. The inlet end of the HWG is connected to the first reservoir. Liquid from the first reservoir flows into the HWG through the inlet end. A second reservoir is connected to the outlet end of the HWG. The second reservoir includes a discharge port. A fluid path connects the first and second reservoirs and bypasses the HWG. The kitchen appliance is operable for both pressurized brew/heat cycles and un-pressurized brew/heat cycles.

Inventors:  Patrick T. Mulvaney (Richmond), Adam Hanes (Glen Allen, Va.), William D. Starr (Richmond)

Assignee:  Hamilton Beach Brands Inc. (Glen Allen, Va.)

Oct. 24, 2017

Container device for tobacco articles

Patent No. 9,795,165

Some embodiments of a tobacco product package device can be used to enhance freshness and other characteristics of tobacco products or other products contained therein. Certain features can improve product freshness both during shelf life and during consumer use.

Inventors:  David Karl Bried (Brentwood, Tenn.), James Arthur Strickland (Richmond), Mark T. Nielsen (Nicholasville, Ky.), Frank Scott Atchley (Midlothian, Va.), Lamar Eugene Walters II (Brentwood, Tenn.), Gregory A. Pace (Nunnelly, Tenn.)

Assignee:  U.S. Smokeless Tobacco Co. (Richmond)

Oct. 24, 2017

Polyelectrolyte complexes

Patent No. 9,796,872

The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellancy, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions where the one polyelectrolyte present in molar excess is added in the form of a first aqueous solution during a mixing step to a second aqueous solution comprising the oppositely charged polyelectrolyte present in molar deficiency. Also provided are means to form stable associative polyelectrolyte complexes in aqueous solutions having R values from about 0.10 to 20, including near stoichiometric R values approaching 1, being the ratio of charged groups present on the component polyelectrolytes employed.

Inventors:  David R. Scheuing (Pleasanton, Calif.), David J. Lestage (McKinney, Texas), Carl W. Bennett (Glen Allen, Va.), Mona M. Knock (Pleasanton, Calif.), Charles W. Scales (St. Augustine, Fla.), William L. Smith (Pleasanton, Calif.), Rui Zhang (Kaohsiung, Taiwan)

Assignee:  The Clorox Co. (Oakland, Calif.)

Oct. 24, 2017

Popcorn maker

Patent No. 9,795,158

A kitchen appliance for popping popcorn comprises a housing and a popping mechanism. The housing comprises a bottom housing portion adapted to sit stably upon a surface during operation of the appliance and adapted to receive popcorn that has been popped by the appliance and a top housing portion adapted to sit stably upon the bottom housing portion during operation of the appliance and selectively removable from the bottom housing portion. The popping mechanism heats unpopped popcorn kernels in order to cause the unpopped popcorn kernels to pop. The popping mechanism is affixed within the top housing portion such that, when the top housing portion is selectively removed from the bottom housing portion and placed upright on a surface, the popping mechanism does not contact the surface.

Inventors:  Drew Carlson (Henrico, Va.), Derek A. McCullough (Henrico, Va.)

Assignee:  Hamilton Beach Brands Inc. (Glen Allen, Va.)

Oct. 24, 2017

Medical injector simulation device

Patent No. 9,805,620

An apparatus includes a simulated medicament delivery device and an electronic circuit system coupled to the simulated medicament delivery device. The electronic circuit system is configured to output an electronic output associated with a use of the simulated medicament delivery device.

Inventors:  Eric S. Edwards (Mosely, Va.), Evan T. Edwards (Charlottesville, Va.), Mark J. Licata (Doswell, Va.), Paul F. Meyers  (Fishers, Ind.), T. Spencer Williamson (Richmond), Kai R. Worrell (Hopkins, Minn.), David A. Weinzierl (Andover, Minn.)

Assignee:  kaleo Inc. (Richmond)

Oct. 31, 2017

Phenylephrine-containing liquid formulations

Patent No. 9,801,941

An oral, aqueous-based, liquid pharmaceutical composition is provided. The composition comprises up to about 45% glycerin and up to about 10% sorbitol wherein the glycerin to sorbitol ratio is about 2:1 to 10:1.

Inventors:  Amanda Alley (Midlothian, Va.), William Bubnis (Mechanicsville, Va.), Stephanie Shield (Richmond)

Assignee:  Wyeth (New York, N.Y.)

Oct. 31, 2017

Supported catalyst particles for oxidizing carbon monoxide

Patent No. 9,801,410

A method for oxidizing carbon monoxide to carbon dioxide is provided which utilizes specific supported catalyst particles. The supported catalyst comprises catalyst particles that are supported on particles of an electrically conductive support selected from the group consisting of graphitic carbon and a partially reduced oxide of a transition metal of the Magneli phase selected from the group consisting of titanium, vanadium, zirconium, niobium, molybdenum, and mixtures thereof.

Inventors:  Donald Miser (Chesterfield, Va.), Diane Gee (Richmond)

Assignee:  Philip Morris USA Inc. (Richmond)

Oct. 31, 2017

Shift significand of decimal floating point data

Patent No. 9,804,823

A decimal floating point finite number in a decimal floating point format is composed from the number in a different format. A decimal floating point format includes fields to hold information relating to the sign, exponent and significand of the decimal floating point finite number. Other decimal floating point data, including infinities and NaNs (not a number), are also composed. Decimal floating point data are also decomposed from the decimal floating point format to a different format. For composition and decomposition, one or more instructions may be employed, including a shift significand instruction.

Inventors:  Shawn D. Lundvall (Midlothian, Va.), Eric M. Schwarz (Gardiner, N.Y.), Ronald M. Smith Sr. (Wappingers Falls, N.Y.), Phil C. Yeh (Poughkeepsie, N.Y.)

Assignee:  International Business Machines Corp. (Armonk, N.Y.)

Oct. 31, 2017

Systems and methods for percutaneous intravascular access and guidewire placement

Patent No. 9,801,653

A device for allowing passage of a guidewire from a primary blood vessel to an adjacent secondary blood vessel includes a main body having a primary lumen and a secondary lumen, and a piercing member disposed in the secondary lumen, and configured to be moved distally out of the secondary lumen, and to pierce through tissue while being distally moved. A third lumen located within the piercing member is configured to allow placement of a guidewire from the primary blood vessel to the adjacent secondary blood vessel. In one embodiment, the secondary lumen is configured to allow articulation of the distal end of the piercing element. The piercing member has a sharp point on one end to facilitate cutting a small communicating aperture from the primary blood vessel to the secondary blood vessel.

Inventors:  Brad M. Kellerman (Escondido, Calif.), Jeffrey E. Hull (Midlothian, Va.), David K. Wrolstad (Yucaipa, Calif.)

Assignee:  Avenu Medical Inc. (San Juan Capistrano, Calif.)

Oct. 31, 2017

Unnatural reactive amino acid genetic code additions

Patent No. 9,797,908

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Inventors: Alexander Deiters (La Jolla, Calif.), T. Ashton Cropp (Richmond), Jason W. Chin (Cambridge, Great Britain),  J. Christopher Anderson (San Francisco, Calif.), Peter G. Schultz (La Jolla, Calif.)

Assignee:  The Scripps Research Institute (La Jolla, Calif.)

Oct. 24, 2017

Intimate blends of carbon-containing and dyeable fibers

Patent No. 9,797,070

An intimate blend of staple fibers, and a yarn, fabric, and article of clothing providing surprising arc performance and coloration capability, comprising a mixture of a first staple fiber made from a flame resistant polymer that retains at least 90 percent of its weight when heated to 425 degrees Celsius at a rate of 10 degrees per minute and comprises 0.5 to 20 weight percent discrete homogeneously dispersed carbon particles; and either (a) a second staple fiber from a flame resistant polymer being free of discrete carbon particles and having an L* lightness coordinate of 70 or greater and being capable of accepting a dye or coloration, or (b) a second staple fiber blend being free of discrete carbon particles and comprising at least one second staple fiber from a flame resistant polymer and having an L* lightness coordinate of 70 or greater and being capable of accepting a dye or coloration; the mixture having a total content of 0.5 to 3 weight percent discrete carbon particles.

Inventors:  Christopher William Newton (Richmond), Reiyao Zhu (Moseley, Va.)

Assignee:  E I Du Pont De Nemours and Co. (Wilmington, Del.)

Oct. 24, 2017

Compositions comprising C5 and C6 oligosaccharides

Patent No. 9,797,021

Compositions comprising C5 and C6 saccharides of varying degrees of polymerization and low levels of undesirable impurities, such as compounds containing sulfur, nitrogen, or metals, are disclosed.

Inventors:  Daniel Clay Floyd (Richmond), Kiran Kadam (Golden, Colo.), Srinivas Kilambi (Duluth, Ga.)

Assignee:  Renmatix Inc. (King of Prussia, Pa.)

Oct. 24, 2017

Kitchen appliance for preparing a beverage and method of operating same

Patent No. 9,795,245

A kitchen appliance includes a first reservoir for receiving a liquid to be used for preparing a beverage and a hot water generator (`HWG`) which has an inlet end, an outlet end and a passageway there between. The inlet end of the HWG is connected to the first reservoir. Liquid from the first reservoir flows into the HWG through the inlet end. A second reservoir is connected to the outlet end of the HWG. The second reservoir includes a discharge port. A fluid path connects the first and second reservoirs and bypasses the HWG. The kitchen appliance is operable for both pressurized brew/heat cycles and un-pressurized brew/heat cycles.

Inventors:  Patrick T. Mulvaney (Richmond), Adam Hanes (Glen Allen, Va.), William D. Starr (Richmond)

Assignee:  Hamilton Beach Brands Inc. (Glen Allen, Va.)

Oct. 24, 2017

Container device for tobacco articles

Patent No. 9,795,165

Some embodiments of a tobacco product package device can be used to enhance freshness and other characteristics of tobacco products or other products contained therein. Certain features can improve product freshness both during shelf life and during consumer use.

Inventors:  David Karl Bried (Brentwood, Tenn.), James Arthur Strickland (Richmond), Mark T. Nielsen (Nicholasville, Ky.), Frank Scott Atchley (Midlothian, Va.), Lamar Eugene Walters II (Brentwood, Tenn.), Gregory A. Pace (Nunnelly, Tenn.)

Assignee:  U.S. Smokeless Tobacco Co. (Richmond)

Oct. 24, 2017

Polyelectrolyte complexes

Patent No. 9,796,872

The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellancy, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions where the one polyelectrolyte present in molar excess is added in the form of a first aqueous solution during a mixing step to a second aqueous solution comprising the oppositely charged polyelectrolyte present in molar deficiency. Also provided are means to form stable associative polyelectrolyte complexes in aqueous solutions having R values from about 0.10 to 20, including near stoichiometric R values approaching 1, being the ratio of charged groups present on the component polyelectrolytes employed.

Inventors:  David R. Scheuing (Pleasanton, Calif.), David J. Lestage (McKinney, Texas), Carl W. Bennett (Glen Allen, Va.), Mona M. Knock (Pleasanton, Calif.), Charles W. Scales (St. Augustine, Fla.), William L. Smith (Pleasanton, Calif.), Rui Zhang (Kaohsiung, Taiwan)

Assignee:  The Clorox Co. (Oakland, Calif.)

Oct. 24, 2017

Popcorn maker

Patent No. 9,795,158

A kitchen appliance for popping popcorn comprises a housing and a popping mechanism. The housing comprises a bottom housing portion adapted to sit stably upon a surface during operation of the appliance and adapted to receive popcorn that has been popped by the appliance and a top housing portion adapted to sit stably upon the bottom housing portion during operation of the appliance and selectively removable from the bottom housing portion. The popping mechanism heats unpopped popcorn kernels in order to cause the unpopped popcorn kernels to pop. The popping mechanism is affixed within the top housing portion such that, when the top housing portion is selectively removed from the bottom housing portion and placed upright on a surface, the popping mechanism does not contact the surface.

Inventors:  Drew Carlson (Henrico, Va.), Derek A. McCullough (Henrico, Va.)

Assignee:  Hamilton Beach Brands Inc. (Glen Allen, Va.)

Oct. 24, 2017

Medical injector simulation device

Patent No. 9,805,620

An apparatus includes a simulated medicament delivery device and an electronic circuit system coupled to the simulated medicament delivery device. The electronic circuit system is configured to output an electronic output associated with a use of the simulated medicament delivery device.

Inventors:  Eric S. Edwards (Mosely, Va.), Evan T. Edwards (Charlottesville, Va.), Mark J. Licata (Doswell, Va.), Paul F. Meyers  (Fishers, Ind.), T. Spencer Williamson (Richmond), Kai R. Worrell (Hopkins, Minn.), David A. Weinzierl (Andover, Minn.)

Assignee:  kaleo Inc. (Richmond)

Oct. 31, 2017

Phenylephrine-containing liquid formulations

Patent No. 9,801,941

An oral, aqueous-based, liquid pharmaceutical composition is provided. The composition comprises up to about 45% glycerin and up to about 10% sorbitol wherein the glycerin to sorbitol ratio is about 2:1 to 10:1.

Inventors:  Amanda Alley (Midlothian, Va.), William Bubnis (Mechanicsville, Va.), Stephanie Shield (Richmond)

Assignee:  Wyeth (New York, N.Y.)

Oct. 31, 2017

Supported catalyst particles for oxidizing carbon monoxide

Patent No. 9,801,410

A method for oxidizing carbon monoxide to carbon dioxide is provided which utilizes specific supported catalyst particles. The supported catalyst comprises catalyst particles that are supported on particles of an electrically conductive support selected from the group consisting of graphitic carbon and a partially reduced oxide of a transition metal of the Magneli phase selected from the group consisting of titanium, vanadium, zirconium, niobium, molybdenum, and mixtures thereof.

Inventors:  Donald Miser (Chesterfield, Va.), Diane Gee (Richmond)

Assignee:  Philip Morris USA Inc. (Richmond)

Oct. 31, 2017

Shift significand of decimal floating point data

Patent No. 9,804,823

A decimal floating point finite number in a decimal floating point format is composed from the number in a different format. A decimal floating point format includes fields to hold information relating to the sign, exponent and significand of the decimal floating point finite number. Other decimal floating point data, including infinities and NaNs (not a number), are also composed. Decimal floating point data are also decomposed from the decimal floating point format to a different format. For composition and decomposition, one or more instructions may be employed, including a shift significand instruction.

Inventors:  Shawn D. Lundvall (Midlothian, Va.), Eric M. Schwarz (Gardiner, N.Y.), Ronald M. Smith Sr. (Wappingers Falls, N.Y.), Phil C. Yeh (Poughkeepsie, N.Y.)

Assignee:  International Business Machines Corp. (Armonk, N.Y.)

Oct. 31, 2017

Systems and methods for percutaneous intravascular access and guidewire placement

Patent No. 9,801,653

A device for allowing passage of a guidewire from a primary blood vessel to an adjacent secondary blood vessel includes a main body having a primary lumen and a secondary lumen, and a piercing member disposed in the secondary lumen, and configured to be moved distally out of the secondary lumen, and to pierce through tissue while being distally moved. A third lumen located within the piercing member is configured to allow placement of a guidewire from the primary blood vessel to the adjacent secondary blood vessel. In one embodiment, the secondary lumen is configured to allow articulation of the distal end of the piercing element. The piercing member has a sharp point on one end to facilitate cutting a small communicating aperture from the primary blood vessel to the secondary blood vessel.

Inventors:  Brad M. Kellerman (Escondido, Calif.), Jeffrey E. Hull (Midlothian, Va.), David K. Wrolstad (Yucaipa, Calif.)

Assignee:  Avenu Medical Inc. (San Juan Capistrano, Calif.)

Oct. 31, 2017

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