Systems and methods for dynamic granular access permissions
Patent No. 10,848,498
An application for dynamic, granular access permissions can include a database interface, a user interface, a login process, an administrator, an event handler and an authorization process. The database interface can be an interface to an access control permissions database that stores roles, actions, or policies for users of the application. The login process can authenticate a user and determine a default set of access control permissions for that user when they are using the user interface. The administrator can provide access control permissions for a user by using the database interface. The event handler can dynamically modify access to functionality in the user interface based on an event. The authorization process can determine whether a request from the user interface is authorized before process the request. The authorization process can use access control permissions from the administrator and either a scope limited or a temporally limited access permission.
Inventors: Brian Childress (Richmond), Sean Stokely (Richmond)
Assignee: Capital One Services (McLean, Virginia)
Nov. 24, 2020
Group messaging systems and methods
Patent No. 10,848,445
Methods, systems, and apparatuses, including computer programs encoded on a computer storage media, are provided for facilitating group communications. The described embodiments provide a group chat application allowing a user to send multiple types of messages, including decision messages (or interactive message), to one or more group chat recipients. The decision messages may include a question, a number of answer options, and a time limit for response. Such messages may be displayed in a group chat feed to allow group participants to submit responses by selecting or ranking the answer options. Results may be determined from the submitted responses and displayed to the sender of a decision message.
Inventors: Travis Willmann (Richmond)
Assignee: Council Technologies (Dover, Delaware)
Nov. 24, 2020
Systems and methods for generating a 360-degree viewing experience
Patent No. 10,845,943
A system for generating a 360-degree viewing experience may receive a plurality of images of an object from an image capture device, wherein each of the plurality of images corresponds to a different rotational orientation of the object relative to the image capture device. The system may detect, using a first machine learning model, the object in each of the plurality of images. The system may detect, using a second machine learning model, regions associated with identifiable object features in one or more images of the plurality of images. The system may assign feature metadata to the one or more images, the features metadata associated with one or more detected regions of the detected regions of the object in the one or more images. The system may publish, with an application programming interface, the plurality of images and the feature metadata for the 360-degree viewing experience.
Inventors: Omar Ahmed Ansari (Richmond), Clark Barrett Jennings (Richmond)
Assignee: CarMax Business Services (Richmond)
Nov. 24, 2020
Curved classifiers and classification methods
Patent No. 10,845,288
A particle electrical mobility classifier is provided for the classification of particles (e.g., particles less than 1 .mu..eta. in size) based on their electrical mobility. The particle classification zone is curved. In an exemplary embodiment, two metal concentric cylinders, separated by an annular insulation spacer, establish a particle classification zone. A DC electrical field is supplied by the cylinders in the circular classification zone. An example classifier can be operated in different modes such as: (1) as a particle precipitator; (2) as a particle electrical mobility separator, and (3) as a differential mobility classifier. The curved classification zone results in a particle classifier having an extended particle sizing range as compared to their counterparts in classical configurations. The curve of the classification channel (in the flow direction) may be in any of several configurations (e.g., circular, wavy, spiral, or helical).
Inventors: Daren Chen (Glen Allen, Virginia), Qiaoling Liu (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Nov. 24, 2020
Oil, grease, and moisture resistant paperboard having a natural appearance
Patent No. 10,844,543
A coated paperboard having a natural appearance is disclosed which includes a barrier coating containing substantially no fluorochemical or wax, exhibiting good resistance to oil, grease, and moisture and having no tendency toward blocking.
Inventors: Jiebin Pang (Glen Allen, Virginia), Scott J. Reigel (Columbus, Georgia), Natasha G. Melton (Richmond), Teresa Krug (Henrico, Virginia), Steven Parker (Raleigh, North Carolina), Terry Clark (Columbus, Georgia)
Assignee: WestRock MWV (Atlanta, Georgia)
Nov. 24, 2020
Methods for preparing therapeutically active cells using microfluidics
Patent No. 10,844,353
The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
Inventors: Anthony Ward (Rancho Santa Fe, California), Roberto Campos-Gonzalez (Carlsbad, California), Alison Skelley (Riverside, California), Khushroo Gandhi (Palo Alto, California), Curt Civin (Baltimore, Maryland), James C. Sturm (Princeton, New Jersey), Michael Grisham (Richmond)
Assignee: GPB Scientific (Richmond) & The Trustees of Princeton University (Princeton, New Jersey) & University of Maryland, Baltimore (Baltimore, Maryland)
Nov. 24, 2020
Modified polyethylene resins and method for making the same
Patent No. 10,844,210
A method for increasing the melt strength and/or low shear viscosity of a polyethylene resin, the method comprising: a) providing a first polyethylene resin having a density ranging from 0.900 g/cm.sup.3 to 0.970 g/cm.sup.3, a melt index ranging from 0.01 g/10 min to 30 g/10 min, and at least 0.20 vinyl groups per 1,000 total carbons; b) providing a masterbatch composition comprising a free radical generator and a second polyethylene resin, wherein the free radical generator has a half-life at 220.degree. C. of less than 200 seconds, and a decomposition energy higher than -250 kJ/mol, and wherein the second polyethylene resin has a density ranging from 0.900 g/cm.sup.3 to 0.970 g/cm.sup.3, melt index ranging from 0.01 g/10 min to 100 g/10 min; and c) reacting the first polyethylene resin with the masterbatch composition to form a modified polyethylene resin.
Inventors: Alexander Williamson (Rosharon, Texas), Surya Subramaniam (Richmond), Jorge C. Gomes (Sao Paulo, Brazil)
Assignee: Dow Global Technologies (Midland, Michigan)
Nov. 24, 2020
Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
Patent No. 10,844,089
The sulfated oxysterol 5-cholesten-3.beta., 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided.
Inventors: Shunlin Ren (Richmond), William M.Pandak (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Nov. 24, 2020
Spark plasma sintered polycrystalline diamond
Patent No. 10,843,975
The present disclosure relates a spark plasma sintered polycrystalline diamond and methods of spark plasma sintering leached polycrystalline diamond. Spark plasma sintering produces plasma from a reactant gas found in the pores left by catalyst removal from leached polycrystalline diamond. The plasma forms diamond bonds and/or carbide structures in the pores, which may produce polycrystalline diamond that is has a higher impact strength than the leached polycrystalline diamond or other improved properties.
Inventors: Qi Liang (Richmond), William Brian Atkins (Houston, Texas)
Assignee: Halliburton Energy Services (Houston, Texas)
Nov. 24, 2020
Shear stable lamination adhesive with spray applied activator
Patent No. 10,843,218
An adhesive application apparatus is provided. The apparatus uses a rolled on adhesive applied to a substrate. After roll application, an adhesive activator is sprayed onto the substrate. By spraying an activator onto the substrate after the adhesive is applied, the adhesive may be made tacky for adhesion, but the adhesive used for rolling may be highly stable and slow to dry/cure without said activator, which enhances rolled application effectiveness.
Inventors: Steven E. Adams (Richmond), Andrew T. Sinclair (Richmond), Robert J. Rose (Richmond, California), Ian L. Churcher (Richmond)
Assignee: Worthen Industries (Nashua, New Hampshire)
Nov. 24, 2020
AipA, OmpA, and Asp14 in vaccine compositions and diagnostic targets for Anaplasma phagocytophilum infection
Patent No. 10,842,860
Anaplasma phagocytophilum surface protein AipA and/or fragments thereof which comprise an invasin domain are used in compositions suitable to elicit an immune response to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. AipA proteins and protein fragments or antibodies directed to AipA proteins and protein fragments are also used in diagnostic assays to detect exposure to and/or infection with Anaplasmatacaea. AipA and/or fragments thereof are also used for these purposes in combination with one or both of Asp14 and OmpA proteins and/or fragments thereof which comprise an invasin domain. Homologs of these proteins are also used in the compositions and assays.
Inventors: Jason Carlyon (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Nov. 24, 2020
Non-combustible smoking device and elements thereof
Patent No. 10,842,193
At least one example embodiment discloses a pre-vapor formulation reservoir configured to contain a pre-vapor formulation material, a heating element coupled to the pre-vapor formulation reservoir and configured to heat at least a portion of the pre-vapor formulation material into a generated vapor and provide the generated vapor to a first portion of a channel, a tobacco housing at a second portion of the channel and positioned to receive the generated vapor, the tobacco housing including tobacco and at least one air flow element in the tobacco housing to direct at least a first portion of the generated vapor towards an end of the non-combustible smoking element.
Inventors: Buket Sahin (Richmond), San Li (Midlothian, Virginia)
Assignee: Altria Client Services (Richmond)
Nov. 24, 2020
Systems and methods for context development
Patent No. 10,848,451
Disclosed are methods, systems, and non-transitory computer-readable medium for context development. For instance, a first method may include obtaining first micro-application actor information associated with a first micro-application actor. The first micro-application actor information may include information for workflow rules, and the workflow rules may include data set rules, extract, transform, load (ETL) rules, and functional expressions. The first method may further include obtaining data from data sources based on the data set rules; applying the ETL rules to the obtained data to generate processed data; applying the functional expressions to the processed data to obtain an output; and performing at least one processing action based on the output. A second method may include generating a system component corresponding to a blueprint based on a user request; associating the system component with a domain of a user account; and performing processes associated the system component.
Inventors: Patrick Moore (Allen, Texas), Colleen Frank (Arlington, Virginia), Venkata Mandali (Glen Allen, Virginia), Bradley Criqui (Chesterfiel, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Nov. 24, 2020
Automation of platform release
Patent No. 10,846,210
Aspects described herein may relate to methods, systems, and apparatuses that combine one or more versions of different software application components of a software platform with a new version of a software component in order to perform an integration test. The combination may be tested in an integration test plan by utilizing versions of the one or more versions of different software application components of the software platform that previously passed the integration test plan. Notification of a failure of the integration testing may be sent back to an applicable developer for correction while the one or more versions of different software application components are maintained.
Inventors: Bijender Singh (Glen Allen, Virginia), Srinivas Alladi (Glen Allen, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Nov. 24, 2020
Droplet-based microfluidic rheometer system
Patent No. 10,845,284
A droplet-based microfluidic rheometer system and method of use for real-time viscosity monitoring of blood coagulation is disclosed. Droplets of blood samples are generated in a microfluidic rheometer, and the size of the droplets is highly correlated to the sample viscosity. The size of the droplets can be determined optically using an inverted light microscope and a camera or using electrodes. The microfluidic rheometer systems provides viscosity measurements in less than a second and consumes less than 1.mu.{umlaut over ()} blood or plasma over an hour period. The viscosity measurements may be displayed and transmitted to the Internet or cloud storage.
Inventors: Yunzi Li (Ann Arbor, Michigan), Kevin R. Ward (Glen Allen, Virginia), Mark A. Burns (Ann Arbor, Michigan)
Assignee: Regents of the University of Michigan (Ann Arbor, Michigan)
Nov. 24, 2020
Medicament delivery device and methods for delivering drugs to infants and children
Patent No. 10,842,938
A method of delivering epinephrine includes placing a distal end surface of a medical injector into contact with a target location of a patient. The medical injector includes a housing, an energy storage member, and a medicament container containing a dose of epinephrine effective for administration to the patient experiencing anaphylaxis and having a weight of less than 15 kg. The medicament container is coupled to a needle. The medical injector is actuated such that the energy storage member produces a force to move the needle from a first needle position to a second needle position. A distal tip of the needle extends from the distal end surface by a distance of between 7 millimeters and 8 millimeters when the needle is in the second needle position. A portion of the force is exerted to expel the dose of epinephrine when the needle is in the second position.
Inventors: Eric S. Edwards (Moseley, Virginia), Evan T. Edwards (Charlottesville, Virginia), Glen L. Kelley (Glen Allen, Virginia), Paul F. Meyers (Fishers, Indiana)
Assignee: kaleo (Richmond)
Nov. 24, 2020
Sheet-metal ammunition packing tray
Patent No. 10,845,174
An ammunition tray is provided for containing a plurality of bullet cartridges within an ammunition box container having a stowage volume. The tray includes a substantially rectangular template having a horizontal surface bounded by first and second opposing longitudinal edges and opposing lateral edges joined at four corners. Each longitudinal edge includes a first tab bent substantially perpendicular to the surface in a vertical direction to form a rib. Each lateral edge includes a second tab bent substantially perpendicular to the surface to form a wall. The surface includes a first row of interior pockets that point towards the first longitudinal edge as a proximal orientation. The surface further includes a second row of interior pockets that point towards the second longitudinal edge as a distal orientation. The template has longitudinal and lateral edges bent to form the respective ribs and walls fits within the stowage volume as a vertical stack of plural templates. Each first interior pocket in the first row can cradle a cartridge on the surface along the proximal orientation, can fit the cartridge from an adjacent second row, and has lateral edges bent to curl in said vertical direction. Each second interior pocket in the second row can cradle the cartridge on the surface along the distal orientation, can fit the cartridge from an adjacent first row, and has lateral edges bent to curl opposite said vertical direction.
Inventors: Gregory D. Little (Ashland, Virginia), John-Paul Shebalin (Chapel Hill, North Carolina), James S. Fetsko (Fredericksburg, Virginia), Joseph A. Silber (King George, Virginia), Christopher N. Davidson (King George, Virginia), John E. Brough (Fredericksburg, Virginia)
Assignee: United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
Nov. 24, 2020
System and method for structural inspection and construction estimation using an unmanned aerial vehicle
Patent No. 10,853,931
An automated image capturing and processing system and method may allow a field user to operate a UAV via a mobile computing device to capture images of a structure area of interest (AOI). The mobile computing device receives user and/or third party data and creates UAV control data and a flight plan. The mobile computing device executes a flight plan by issuing commands to the UAV’s flight and camera controller that allows for complete coverage of the structure AOI. After data acquisition, the mobile computing device then transmits the UAV output data to a server for further processing. At the server, the UAV output data can be used for a three-dimensional reconstruction process. The server then generates a vector model from the images that precisely represents the dimensions of the structure. The server can then generate a report for inspection and construction estimation.
Inventors: Martin Marra (Louisville, Colorado), James F. Smyth (Richmond)
Assignee: EZ3D Technologies (Syracuse, New York)
Dec. 1, 2020
Method and system for authorizing card account transactions by geographic region
10,853,815
A method and system for authorizing card account transactions by geographic region by providing data for a user interface displaying geographic regions and merchant locations each corresponding to the location of a merchant where a transaction using a card account may be initiated, receiving a user interface selection representing a request to authorize or restrict card account transactions, receiving authorization requests for desired transactions, and authorizing or restricting the transactions in accordance with the request.
Inventors: Michele D. Matthews (Richmond)
Assignee: Capital One Services (McLean, Virginia)
Dec. 1, 2020
Secure authentication based on identity data stored in a contactless card
Patent No. 10,853,795
Systems, methods, articles of manufacture, and computer-readable media for secure authentication based on identity data stored in a contactless card associated with an account. An application may receive an indication specifying to perform an operation. The application may receive encrypted data from the card, the encrypted data based on a cryptographic algorithm, a customer identifier, and a private key. The application may receive an indication that the authentication server verified the encrypted data based on the private key for the card. The application may determine a type of data required to authorize the operation. The application may receive data comprising passport data or driver license data from the card. The application may determine that the data satisfies a rule for authorizing the operation and authorize performance of the operation based on the authentication server verifying the encrypted data and the data satisfying the at least one rule.
Inventors: Nicholas Capurso (Tysons Corner, Virginia), Samuel Edwards (Richmond), Jason Pribble (McLean, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Dec. 1, 2020
Airflow puff topography measurement device and method
Patent No. 10,849,361
Provided herein is a device for measuring puff topography generated by a human user of a smoking device and methods for using the same. The device may be used for research on puffing behavior of tobacco product users in both clinical and non-clinical settings.
Inventors: Alan Shihadeh (Beirut, Lebanon), Thomas Eissenberg (Richmond)
Assignee: Virginia Commonwealth University (Richmond) & American University of Beirut (Beirut, Lebanon)
Dec. 1, 2020
E-vaping cartridge
Patent No. 10,849,358
An e-vaping cartridge includes an inner tube defining a channel. A heater is positioned near a first end of the channel, and a hydrogel is located near a second end of the channel. The hydrogel includes a flavorant that releases flavors and/or aromas to the vapor as the vapor passes the hydrogel.
Inventors: Munmaya K. Mishra (Manakin Sabot, Virginia), Shaoyong Yu (Henrico, Virginia), Raymond Lau (Glen Allen, Virginia), Pauline Marcq (Richmond)
Assignee: Altria Client Services (Richmond)
Dec. 1, 2020
Tobacco having altered leaf properties and methods of making and using
Patent No. 10,851,384
This disclosure provides tobacco plants having a mutation in PR50 and transgenic tobacco plants containing a PR50 RNAi, and methods of making and using such plants.
Inventors: Chengalrayan Kudithipudi (Midlothian, Virginia), Alec J. Hayes (Chesterfield, Virginia)
Assignee: Altria Client Services (Richmond, Virginia)
Dec. 1, 2020
Modular cardiac rhythm management using Q to LV activation measures
Patent No. 10,849,522
Methods and systems for use of the Q-wave to R-wave interval to guide placement of a leadless cardiac pacemaker are disclosed. An implant delivery device is equipped with sensing electrodes to sense R-wave onset in a ventricle of a patient’s heart to allow placement at a location of last or latest onset of the R-wave. Guidance tools are provided to assist in determination of the Q-wave to R-wave interval during implantation. For a chronic system, a cooperative approach is disclosed in which an implantable medical device and a leadless cardiac pacemaker exchange data to determine Q-wave to R-wave intervals and enhance cardiac resynchronization therapy delivery by the leadless cardiac pacemaker.
Inventors: Steven Lee Eddy (Chesterfield, Virginia), Brendan Early Koop (Ham Lake, Minnesota), Yinghong Yu (Shoreview, Minnesota)
Assignee: Cardiac Pacemakers (St. Paul, Minnesota)
Dec. 1, 2020
Grafted polymer with soot handling properties
Patent No. 10,851,324
The present disclosure relates to oxazoline modified lubricant additives that have dispersant properties and lubricating oil compositions comprising said dispersant lubricant additives. The disclosure also relates to the use of lubricant compositions comprising the additives of the disclosure for improving the soot or sludge handling characteristics of an engine lubricant composition, while minimizing the deterioration of engine seals.
Inventors: Sheng Jiang (Glen Allen, Virginia), Arturo Carranza (Henrico, Virginia)
Assignee: Afton Chemical Corp. (Richmond)
Dec. 1, 2020
Vapor-permeable, substantially water-impermeable multilayer article
Patent No. 10,850,491
This disclosure relates to an article that includes a nonwoven substrate, a first film supported by the nonwoven substrate, and a second film such that the first film is between the nonwoven substrate and the second film. The first film includes a first polymer and a pore-forming filler. The difference between a surface energy of the first film and a surface energy of the nonwoven substrate is at most about 10 mN/m. The second film includes a second polymer capable of absorbing and desorbing moisture and providing a barrier to aqueous fluids.
Inventors: Mehdi Afshari (Midlothian, Virginia)
Assignee: Fiberweb (Wilmington, Delaware)
Dec. 1, 2020
Systems and methods for secure remote identity verification
Patent No. 10,855,471
Systems and methods are provided for authenticating an identity of a user requesting a resource or service from an entity. In some embodiments, a system may include at least one processor; and a non-transitory medium containing instructions that cause the system to perform operations. The operations may include receiving credential information associated with the remote user, and receiving, from the server associated with the entity, first hash information. The operations may also include generating second hash information based on information associated with the user, comparing the first hash information with the second hash information, and transmitting an indication based on the comparison to the server associated with the entity.
Inventors: Ryan Fox (Lebanon, Ohio), Jonathan Weimer (Henrico, Virginia), Meghnath Sharma (Chantilly, Virginia), Charles W. Hall (Manakin-Sabot, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Dec. 1, 2020
Systems and methods for dynamic granular access permissions
Patent No. 10,848,498
An application for dynamic, granular access permissions can include a database interface, a user interface, a login process, an administrator, an event handler and an authorization process. The database interface can be an interface to an access control permissions database that stores roles, actions, or policies for users of the application. The login process can authenticate a user and determine a default set of access control permissions for that user when they are using the user interface. The administrator can provide access control permissions for a user by using the database interface. The event handler can dynamically modify access to functionality in the user interface based on an event. The authorization process can determine whether a request from the user interface is authorized before process the request. The authorization process can use access control permissions from the administrator and either a scope limited or a temporally limited access permission.
Inventors: Brian Childress (Richmond), Sean Stokely (Richmond)
Assignee: Capital One Services (McLean, Virginia)
Nov. 24, 2020
Group messaging systems and methods
Patent No. 10,848,445
Methods, systems, and apparatuses, including computer programs encoded on a computer storage media, are provided for facilitating group communications. The described embodiments provide a group chat application allowing a user to send multiple types of messages, including decision messages (or interactive message), to one or more group chat recipients. The decision messages may include a question, a number of answer options, and a time limit for response. Such messages may be displayed in a group chat feed to allow group participants to submit responses by selecting or ranking the answer options. Results may be determined from the submitted responses and displayed to the sender of a decision message.
Inventors: Travis Willmann (Richmond)
Assignee: Council Technologies (Dover, Delaware)
Nov. 24, 2020
Systems and methods for generating a 360-degree viewing experience
Patent No. 10,845,943
A system for generating a 360-degree viewing experience may receive a plurality of images of an object from an image capture device, wherein each of the plurality of images corresponds to a different rotational orientation of the object relative to the image capture device. The system may detect, using a first machine learning model, the object in each of the plurality of images. The system may detect, using a second machine learning model, regions associated with identifiable object features in one or more images of the plurality of images. The system may assign feature metadata to the one or more images, the features metadata associated with one or more detected regions of the detected regions of the object in the one or more images. The system may publish, with an application programming interface, the plurality of images and the feature metadata for the 360-degree viewing experience.
Inventors: Omar Ahmed Ansari (Richmond), Clark Barrett Jennings (Richmond)
Assignee: CarMax Business Services (Richmond)
Nov. 24, 2020
Curved classifiers and classification methods
Patent No. 10,845,288
A particle electrical mobility classifier is provided for the classification of particles (e.g., particles less than 1 .mu..eta. in size) based on their electrical mobility. The particle classification zone is curved. In an exemplary embodiment, two metal concentric cylinders, separated by an annular insulation spacer, establish a particle classification zone. A DC electrical field is supplied by the cylinders in the circular classification zone. An example classifier can be operated in different modes such as: (1) as a particle precipitator; (2) as a particle electrical mobility separator, and (3) as a differential mobility classifier. The curved classification zone results in a particle classifier having an extended particle sizing range as compared to their counterparts in classical configurations. The curve of the classification channel (in the flow direction) may be in any of several configurations (e.g., circular, wavy, spiral, or helical).
Inventors: Daren Chen (Glen Allen, Virginia), Qiaoling Liu (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Nov. 24, 2020
Oil, grease, and moisture resistant paperboard having a natural appearance
Patent No. 10,844,543
A coated paperboard having a natural appearance is disclosed which includes a barrier coating containing substantially no fluorochemical or wax, exhibiting good resistance to oil, grease, and moisture and having no tendency toward blocking.
Inventors: Jiebin Pang (Glen Allen, Virginia), Scott J. Reigel (Columbus, Georgia), Natasha G. Melton (Richmond), Teresa Krug (Henrico, Virginia), Steven Parker (Raleigh, North Carolina), Terry Clark (Columbus, Georgia)
Assignee: WestRock MWV (Atlanta, Georgia)
Nov. 24, 2020
Methods for preparing therapeutically active cells using microfluidics
Patent No. 10,844,353
The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
Inventors: Anthony Ward (Rancho Santa Fe, California), Roberto Campos-Gonzalez (Carlsbad, California), Alison Skelley (Riverside, California), Khushroo Gandhi (Palo Alto, California), Curt Civin (Baltimore, Maryland), James C. Sturm (Princeton, New Jersey), Michael Grisham (Richmond)
Assignee: GPB Scientific (Richmond) & The Trustees of Princeton University (Princeton, New Jersey) & University of Maryland, Baltimore (Baltimore, Maryland)
Nov. 24, 2020
Modified polyethylene resins and method for making the same
Patent No. 10,844,210
A method for increasing the melt strength and/or low shear viscosity of a polyethylene resin, the method comprising: a) providing a first polyethylene resin having a density ranging from 0.900 g/cm.sup.3 to 0.970 g/cm.sup.3, a melt index ranging from 0.01 g/10 min to 30 g/10 min, and at least 0.20 vinyl groups per 1,000 total carbons; b) providing a masterbatch composition comprising a free radical generator and a second polyethylene resin, wherein the free radical generator has a half-life at 220.degree. C. of less than 200 seconds, and a decomposition energy higher than -250 kJ/mol, and wherein the second polyethylene resin has a density ranging from 0.900 g/cm.sup.3 to 0.970 g/cm.sup.3, melt index ranging from 0.01 g/10 min to 100 g/10 min; and c) reacting the first polyethylene resin with the masterbatch composition to form a modified polyethylene resin.
Inventors: Alexander Williamson (Rosharon, Texas), Surya Subramaniam (Richmond), Jorge C. Gomes (Sao Paulo, Brazil)
Assignee: Dow Global Technologies (Midland, Michigan)
Nov. 24, 2020
Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
Patent No. 10,844,089
The sulfated oxysterol 5-cholesten-3.beta., 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided.
Inventors: Shunlin Ren (Richmond), William M.Pandak (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Nov. 24, 2020
Spark plasma sintered polycrystalline diamond
Patent No. 10,843,975
The present disclosure relates a spark plasma sintered polycrystalline diamond and methods of spark plasma sintering leached polycrystalline diamond. Spark plasma sintering produces plasma from a reactant gas found in the pores left by catalyst removal from leached polycrystalline diamond. The plasma forms diamond bonds and/or carbide structures in the pores, which may produce polycrystalline diamond that is has a higher impact strength than the leached polycrystalline diamond or other improved properties.
Inventors: Qi Liang (Richmond), William Brian Atkins (Houston, Texas)
Assignee: Halliburton Energy Services (Houston, Texas)
Nov. 24, 2020
Shear stable lamination adhesive with spray applied activator
Patent No. 10,843,218
An adhesive application apparatus is provided. The apparatus uses a rolled on adhesive applied to a substrate. After roll application, an adhesive activator is sprayed onto the substrate. By spraying an activator onto the substrate after the adhesive is applied, the adhesive may be made tacky for adhesion, but the adhesive used for rolling may be highly stable and slow to dry/cure without said activator, which enhances rolled application effectiveness.
Inventors: Steven E. Adams (Richmond), Andrew T. Sinclair (Richmond), Robert J. Rose (Richmond, California), Ian L. Churcher (Richmond)
Assignee: Worthen Industries (Nashua, New Hampshire)
Nov. 24, 2020
AipA, OmpA, and Asp14 in vaccine compositions and diagnostic targets for Anaplasma phagocytophilum infection
Patent No. 10,842,860
Anaplasma phagocytophilum surface protein AipA and/or fragments thereof which comprise an invasin domain are used in compositions suitable to elicit an immune response to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. AipA proteins and protein fragments or antibodies directed to AipA proteins and protein fragments are also used in diagnostic assays to detect exposure to and/or infection with Anaplasmatacaea. AipA and/or fragments thereof are also used for these purposes in combination with one or both of Asp14 and OmpA proteins and/or fragments thereof which comprise an invasin domain. Homologs of these proteins are also used in the compositions and assays.
Inventors: Jason Carlyon (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Nov. 24, 2020
Non-combustible smoking device and elements thereof
Patent No. 10,842,193
At least one example embodiment discloses a pre-vapor formulation reservoir configured to contain a pre-vapor formulation material, a heating element coupled to the pre-vapor formulation reservoir and configured to heat at least a portion of the pre-vapor formulation material into a generated vapor and provide the generated vapor to a first portion of a channel, a tobacco housing at a second portion of the channel and positioned to receive the generated vapor, the tobacco housing including tobacco and at least one air flow element in the tobacco housing to direct at least a first portion of the generated vapor towards an end of the non-combustible smoking element.
Inventors: Buket Sahin (Richmond), San Li (Midlothian, Virginia)
Assignee: Altria Client Services (Richmond)
Nov. 24, 2020
Systems and methods for context development
Patent No. 10,848,451
Disclosed are methods, systems, and non-transitory computer-readable medium for context development. For instance, a first method may include obtaining first micro-application actor information associated with a first micro-application actor. The first micro-application actor information may include information for workflow rules, and the workflow rules may include data set rules, extract, transform, load (ETL) rules, and functional expressions. The first method may further include obtaining data from data sources based on the data set rules; applying the ETL rules to the obtained data to generate processed data; applying the functional expressions to the processed data to obtain an output; and performing at least one processing action based on the output. A second method may include generating a system component corresponding to a blueprint based on a user request; associating the system component with a domain of a user account; and performing processes associated the system component.
Inventors: Patrick Moore (Allen, Texas), Colleen Frank (Arlington, Virginia), Venkata Mandali (Glen Allen, Virginia), Bradley Criqui (Chesterfiel, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Nov. 24, 2020
Automation of platform release
Patent No. 10,846,210
Aspects described herein may relate to methods, systems, and apparatuses that combine one or more versions of different software application components of a software platform with a new version of a software component in order to perform an integration test. The combination may be tested in an integration test plan by utilizing versions of the one or more versions of different software application components of the software platform that previously passed the integration test plan. Notification of a failure of the integration testing may be sent back to an applicable developer for correction while the one or more versions of different software application components are maintained.
Inventors: Bijender Singh (Glen Allen, Virginia), Srinivas Alladi (Glen Allen, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Nov. 24, 2020
Droplet-based microfluidic rheometer system
Patent No. 10,845,284
A droplet-based microfluidic rheometer system and method of use for real-time viscosity monitoring of blood coagulation is disclosed. Droplets of blood samples are generated in a microfluidic rheometer, and the size of the droplets is highly correlated to the sample viscosity. The size of the droplets can be determined optically using an inverted light microscope and a camera or using electrodes. The microfluidic rheometer systems provides viscosity measurements in less than a second and consumes less than 1.mu.{umlaut over ()} blood or plasma over an hour period. The viscosity measurements may be displayed and transmitted to the Internet or cloud storage.
Inventors: Yunzi Li (Ann Arbor, Michigan), Kevin R. Ward (Glen Allen, Virginia), Mark A. Burns (Ann Arbor, Michigan)
Assignee: Regents of the University of Michigan (Ann Arbor, Michigan)
Nov. 24, 2020
Medicament delivery device and methods for delivering drugs to infants and children
Patent No. 10,842,938
A method of delivering epinephrine includes placing a distal end surface of a medical injector into contact with a target location of a patient. The medical injector includes a housing, an energy storage member, and a medicament container containing a dose of epinephrine effective for administration to the patient experiencing anaphylaxis and having a weight of less than 15 kg. The medicament container is coupled to a needle. The medical injector is actuated such that the energy storage member produces a force to move the needle from a first needle position to a second needle position. A distal tip of the needle extends from the distal end surface by a distance of between 7 millimeters and 8 millimeters when the needle is in the second needle position. A portion of the force is exerted to expel the dose of epinephrine when the needle is in the second position.
Inventors: Eric S. Edwards (Moseley, Virginia), Evan T. Edwards (Charlottesville, Virginia), Glen L. Kelley (Glen Allen, Virginia), Paul F. Meyers (Fishers, Indiana)
Assignee: kaleo (Richmond)
Nov. 24, 2020
Sheet-metal ammunition packing tray
Patent No. 10,845,174
An ammunition tray is provided for containing a plurality of bullet cartridges within an ammunition box container having a stowage volume. The tray includes a substantially rectangular template having a horizontal surface bounded by first and second opposing longitudinal edges and opposing lateral edges joined at four corners. Each longitudinal edge includes a first tab bent substantially perpendicular to the surface in a vertical direction to form a rib. Each lateral edge includes a second tab bent substantially perpendicular to the surface to form a wall. The surface includes a first row of interior pockets that point towards the first longitudinal edge as a proximal orientation. The surface further includes a second row of interior pockets that point towards the second longitudinal edge as a distal orientation. The template has longitudinal and lateral edges bent to form the respective ribs and walls fits within the stowage volume as a vertical stack of plural templates. Each first interior pocket in the first row can cradle a cartridge on the surface along the proximal orientation, can fit the cartridge from an adjacent second row, and has lateral edges bent to curl in said vertical direction. Each second interior pocket in the second row can cradle the cartridge on the surface along the distal orientation, can fit the cartridge from an adjacent first row, and has lateral edges bent to curl opposite said vertical direction.
Inventors: Gregory D. Little (Ashland, Virginia), John-Paul Shebalin (Chapel Hill, North Carolina), James S. Fetsko (Fredericksburg, Virginia), Joseph A. Silber (King George, Virginia), Christopher N. Davidson (King George, Virginia), John E. Brough (Fredericksburg, Virginia)
Assignee: United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
Nov. 24, 2020
System and method for structural inspection and construction estimation using an unmanned aerial vehicle
Patent No. 10,853,931
An automated image capturing and processing system and method may allow a field user to operate a UAV via a mobile computing device to capture images of a structure area of interest (AOI). The mobile computing device receives user and/or third party data and creates UAV control data and a flight plan. The mobile computing device executes a flight plan by issuing commands to the UAV’s flight and camera controller that allows for complete coverage of the structure AOI. After data acquisition, the mobile computing device then transmits the UAV output data to a server for further processing. At the server, the UAV output data can be used for a three-dimensional reconstruction process. The server then generates a vector model from the images that precisely represents the dimensions of the structure. The server can then generate a report for inspection and construction estimation.
Inventors: Martin Marra (Louisville, Colorado), James F. Smyth (Richmond)
Assignee: EZ3D Technologies (Syracuse, New York)
Dec. 1, 2020
Method and system for authorizing card account transactions by geographic region
10,853,815
A method and system for authorizing card account transactions by geographic region by providing data for a user interface displaying geographic regions and merchant locations each corresponding to the location of a merchant where a transaction using a card account may be initiated, receiving a user interface selection representing a request to authorize or restrict card account transactions, receiving authorization requests for desired transactions, and authorizing or restricting the transactions in accordance with the request.
Inventors: Michele D. Matthews (Richmond)
Assignee: Capital One Services (McLean, Virginia)
Dec. 1, 2020
Secure authentication based on identity data stored in a contactless card
Patent No. 10,853,795
Systems, methods, articles of manufacture, and computer-readable media for secure authentication based on identity data stored in a contactless card associated with an account. An application may receive an indication specifying to perform an operation. The application may receive encrypted data from the card, the encrypted data based on a cryptographic algorithm, a customer identifier, and a private key. The application may receive an indication that the authentication server verified the encrypted data based on the private key for the card. The application may determine a type of data required to authorize the operation. The application may receive data comprising passport data or driver license data from the card. The application may determine that the data satisfies a rule for authorizing the operation and authorize performance of the operation based on the authentication server verifying the encrypted data and the data satisfying the at least one rule.
Inventors: Nicholas Capurso (Tysons Corner, Virginia), Samuel Edwards (Richmond), Jason Pribble (McLean, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Dec. 1, 2020
Airflow puff topography measurement device and method
Patent No. 10,849,361
Provided herein is a device for measuring puff topography generated by a human user of a smoking device and methods for using the same. The device may be used for research on puffing behavior of tobacco product users in both clinical and non-clinical settings.
Inventors: Alan Shihadeh (Beirut, Lebanon), Thomas Eissenberg (Richmond)
Assignee: Virginia Commonwealth University (Richmond) & American University of Beirut (Beirut, Lebanon)
Dec. 1, 2020
E-vaping cartridge
Patent No. 10,849,358
An e-vaping cartridge includes an inner tube defining a channel. A heater is positioned near a first end of the channel, and a hydrogel is located near a second end of the channel. The hydrogel includes a flavorant that releases flavors and/or aromas to the vapor as the vapor passes the hydrogel.
Inventors: Munmaya K. Mishra (Manakin Sabot, Virginia), Shaoyong Yu (Henrico, Virginia), Raymond Lau (Glen Allen, Virginia), Pauline Marcq (Richmond)
Assignee: Altria Client Services (Richmond)
Dec. 1, 2020
Tobacco having altered leaf properties and methods of making and using
Patent No. 10,851,384
This disclosure provides tobacco plants having a mutation in PR50 and transgenic tobacco plants containing a PR50 RNAi, and methods of making and using such plants.
Inventors: Chengalrayan Kudithipudi (Midlothian, Virginia), Alec J. Hayes (Chesterfield, Virginia)
Assignee: Altria Client Services (Richmond, Virginia)
Dec. 1, 2020
Modular cardiac rhythm management using Q to LV activation measures
Patent No. 10,849,522
Methods and systems for use of the Q-wave to R-wave interval to guide placement of a leadless cardiac pacemaker are disclosed. An implant delivery device is equipped with sensing electrodes to sense R-wave onset in a ventricle of a patient’s heart to allow placement at a location of last or latest onset of the R-wave. Guidance tools are provided to assist in determination of the Q-wave to R-wave interval during implantation. For a chronic system, a cooperative approach is disclosed in which an implantable medical device and a leadless cardiac pacemaker exchange data to determine Q-wave to R-wave intervals and enhance cardiac resynchronization therapy delivery by the leadless cardiac pacemaker.
Inventors: Steven Lee Eddy (Chesterfield, Virginia), Brendan Early Koop (Ham Lake, Minnesota), Yinghong Yu (Shoreview, Minnesota)
Assignee: Cardiac Pacemakers (St. Paul, Minnesota)
Dec. 1, 2020
Grafted polymer with soot handling properties
Patent No. 10,851,324
The present disclosure relates to oxazoline modified lubricant additives that have dispersant properties and lubricating oil compositions comprising said dispersant lubricant additives. The disclosure also relates to the use of lubricant compositions comprising the additives of the disclosure for improving the soot or sludge handling characteristics of an engine lubricant composition, while minimizing the deterioration of engine seals.
Inventors: Sheng Jiang (Glen Allen, Virginia), Arturo Carranza (Henrico, Virginia)
Assignee: Afton Chemical Corp. (Richmond)
Dec. 1, 2020
Vapor-permeable, substantially water-impermeable multilayer article
Patent No. 10,850,491
This disclosure relates to an article that includes a nonwoven substrate, a first film supported by the nonwoven substrate, and a second film such that the first film is between the nonwoven substrate and the second film. The first film includes a first polymer and a pore-forming filler. The difference between a surface energy of the first film and a surface energy of the nonwoven substrate is at most about 10 mN/m. The second film includes a second polymer capable of absorbing and desorbing moisture and providing a barrier to aqueous fluids.
Inventors: Mehdi Afshari (Midlothian, Virginia)
Assignee: Fiberweb (Wilmington, Delaware)
Dec. 1, 2020
Systems and methods for secure remote identity verification
Patent No. 10,855,471
Systems and methods are provided for authenticating an identity of a user requesting a resource or service from an entity. In some embodiments, a system may include at least one processor; and a non-transitory medium containing instructions that cause the system to perform operations. The operations may include receiving credential information associated with the remote user, and receiving, from the server associated with the entity, first hash information. The operations may also include generating second hash information based on information associated with the user, comparing the first hash information with the second hash information, and transmitting an indication based on the comparison to the server associated with the entity.
Inventors: Ryan Fox (Lebanon, Ohio), Jonathan Weimer (Henrico, Virginia), Meghnath Sharma (Chantilly, Virginia), Charles W. Hall (Manakin-Sabot, Virginia)
Assignee: Capital One Services (McLean, Virginia)
Dec. 1, 2020