Systems And Methods For Synchronization Of Photons Over Quantum Channels With Co-propagating Clock Pulses
Patent No. 11588613
Systems and methods for operating a quantum network system. The methods comprise, by a network node: generating optical clock pulses and photons using the optical clock pulses; generating a combined signal by combining the optical clock pulses with at least some of the photons such that a consistent temporal offset exits between the optical clock pulses and the first photons and/or a wave function of each photon at least partially overlaps an envelope of a respective one of the optical clock pulses; and transmitting the combined signal over a first quantum channel in which the optical clock pulses co-propagate with the photons.
Inventors: Michael C. Garrett (Melbourne, Fla.); James A. Nagel (Fort Wayne, Ind.); Victor G. Bucklew (Richmond); Samuel H. Knarr (Melbourne, Fla.); Cypryan T. Klish (Melbourne, Fla.); Timothy C. Burt (Webster, N.Y.)
Assignee: Eagle Technology (Melbourne, Fla.)
Feb. 21, 2023
Helmet Stabilization Apparatus
Patent No. 11583025
A helmet stabilization system and apparatus for reducing the incidence of whiplash and neck injuries while wearing a helmet, such as in contact sports. The invention includes a helmet mount; a base mount configured for attachment to a shoulder harness; and a flex rod interconnectable between the helmet mount and the base mount. The flex rod, when interconnected between the helmet mount and the base mount provides a resistance to an extension or a compression sequence responsive to a contact imparted on the helmet. An oobleck may be provided in a coupling between the flex rod and the base mount to permit voluntary head movements of the user and to provide a resistance responsive to an impact force.
Inventors: Howard Donal Peace III (Richmond)
Assignee: N/A
Feb. 21, 2023
E-vapor Device Including A Compound Heater Structure
Patent No. 11589427
An e-vapor device may include a pre-vapor sector and a heater structure arranged in thermal contact with the pre-vapor sector. The pre-vapor sector includes a reservoir and a dispensing interface. The pre-vapor sector is configured to hold and dispense a pre-vapor formulation. The heater structure is configured to vaporize the pre-vapor formulation to generate a vapor. The heater structure includes a base wire and a heater wire coiled around the base wire. The base wire is insulated from the heater wire. As a result of the heater design, the heater structure is stiffer and more robust than other related heaters in the art, thus allowing more options for its implementation.
Inventors: Peter Lipowicz (Midlothian, Va.)
Assignee: Altria Client Services (Richmond)
Feb. 21, 2023
Radiolucent, 3-D Printed Soft Tissue Retractor
Patent No. 11583268
A radiolucent, 3-D printed soft tissue retractor includes an elongate, curved support body having a long central axis that exceeds the length of a short, transverse axis. A bone engaging concavity is provided on a first side of the body. A concave soft tissue retracting surface is provided on a second side of the body. An inflection point is provided on the body in between the bone engaging concavity and the soft tissue retracting surface. The soft tissue retractor is configured to cooperate with a second soft tissue retractor and a backing plate to retract tissue and stabilize bones during a surgical distal radius fracture repair.
Assignee: Alidad Ghiassi (Los Angeles, Calif.); Steven Howard (La Jolla, Calif.); Bradley Klos (Solana Beach, Calif.); Michael Bauschard (Richmond)
Assignee: Retractortho (Solana Beach, Calif.)
Feb. 21, 2023
Polymeric Surfactants For Improved Emulsion And Flow Properties At Low Temperatures
Patent No. 11584898
A polymer surfactant for improving engine oil emulsion properties of a lubricating composition mixed with water and/or fuel contamination, particularly at very cold temperatures, is described herein. In approaches, selected polymeric and functionalized compounds can impart both robust emulsion properties and simultaneously deliver good low temperature fluidity for lubricating compositions that may contain residual amounts of water and/or fuel contamination. Lubricating compositions including such surfactants demonstrate robust properties at temperatures down to about −30° C.
Assignee: Yunhai Bai (Richmond); Joseph Remias (Glen Allen, Va.); Yen Tran (Richmond); Amy M. James (Richmond); Kristi Engelman (Richmond)
Assignee: Afton Chemical Corp.
Feb. 21, 2023
Cartridge For An Aerosol-generating System With Customizable Identification Resistance
Patent No. 11589429
In a method of manufacturing a cartridge of an electronic vaping device, wherein the cartridge includes a pre-vapor formulation storage element, an electrical resistor is physically manipulated to change a resistance of the electrical resistor from a first resistance value to a second resistance value, the second resistance value indicative of a pre-vapor formulation substrate contained in the pre-vapor formulation storage element. The electrical resistor is then mounted to a portion of the cartridge.
Assignee: Tony Reevell (London, Great Britain)
Assignee: Altria Client Services (Richmond)
Feb. 21, 2023
Lubricant Formulations With Silicon-containing Compounds
Patent No. 11584897
A lubricating oil composition including a major amount of a base oil, one or more calcium-containing detergents to provide at least 1000 ppmw of calcium, and one or more silicon-containing compound(s) to provide at least 50 ppmw of silicon to the lubricating oil composition, all based on the total weight of the lubricating oil composition, wherein a ratio of ppmw of silicon provided by the one or more silicon-containing compound(s) to the lubricating oil composition to the ppmw of calcium provided by the one or more calcium-containing detergent(s) to the lubricating oil composition is from 0.02 to 1. Methods of using these compositions and silicon-containing detergents are also described.
Inventors: Ashutosh Gupta (Henrico, Va.); Ian Bell (Abingdon, Va.); Kongsheng Yang (Glen Allen, Va.); Alexei Neverov (Chesterfield, Va.); Joseph W. Roos (Mechanicsville, Va.); Joseph Remias (Glen Allen, Va.)
Assignee: Afton Chemical Corp. (Richmond)
Feb. 21, 2023
Collar For A Disposable Surgical Gown
Patent No. 11583013
A collar for a disposable surgical gown is provided. The collar includes a first portion having a first end and second end and a second portion having a first and second end. The first ends of the first portion and the second portion meet at a front of the collar to form a v-neck shape and the second ends of the first portion and the second portion meet at a rear of the collar to define a neck opening. The v-neck shape at the front of the collar forms an angle of greater than 90° at the neck opening, while the second end of the first portion and the second end of the second portion are tapered at the rear of the collar. Such an arrangement prevents the collar from gapping when a wearer leans forward or moves during, for instance, a surgical procedure.
Inventors: Jerald T. Jascomb (Roswell, Ga.)
Assignee: O&M Halyard (Mechanicsville, Va.)
Feb. 21, 2023
Cut And Seal Method And Apparatus
Patent No. 11591128
A fin sealer and method to seal a radially outwardly directed fin of a tubular web structure by directing the fin through a nip between a first and a second fin sealing rollers while communicating heat to the fin through at least one of the fin sealing rollers is provided. The fin sealer is configured to maintain a nominal face-to-face relation between an outer annulus of the first fin sealing roller and an outer annulus of the second fin sealing roller with a flexible connection between a hub element of the second fin sealing roller with the outer annulus of the second fin sealing roller.
Inventors: Jarrod W. Chalkley (Mechanicsville, Va.); James D. Evans (Chesterfield, Va.); Thien Hoang Nguyen (Glen Allen, Va.); Patrick s. McElhinney (Chesterfield, Va.)
Assignee: Altria Client Services (Richmond)
Feb. 28, 2023
Multi-layer Visor System For Surgical Hood
Patent No. 11589633
A multi-layer visor system for a surgical hood or garment is provided. The system includes a base film layer and one or more removable film layers that are coextruded at high temperature to form a sterile surface between each of the film layers should the surgeon elect to peel away a soiled or splattered removable film layer during the course of a surgical procedure so that an unobstructed view can be maintained. Thus, no separate sterilization step is required in order to sterilize the layers of the visor system. Each of the removable film layers can additionally include a tab having distinctive features in order to enable a wearer to easily distinguish between the tabs in order to make it easier for a wearer to know which tab to pull first to remove the outermost removable film layer. Further, because the tabs are located about the perimeter of the removable films, viewing is not obscured, yet the film layers are held securely in place until easily removed from the underlying removable film layer or base film layer.
Inventors: Jerald T. Jascomb (Roswell, Ga.); Namita A. Mithani (Alpharetta, Ga.)
Assignee: O&M Halyard (Mechanicalsville, Va.)
Feb. 28, 2023
Biodegradable Cleaning Composition
Patent No. 11591547
The present invention is directed to biodegradable cleaning compositions, in particular hard surface cleaning compositions, and their use. The compositions according to the invention comprise one or more biosurfactants(s), one or more sorbitan ester(s) and one or more further surfactant(s), which is/are neither a biosurfactant nor a sorbitan ester.
Inventors: Zheng Xue (Henrico, Va.); Andras Nagy (Chester, Va.); Dennis Parrish (Sandston, Va.); Sam Christy (Selbyville, Del.); Jennifer Goodyear (Chester, Va.); Jeff Davidson (Beaverdam, Va.)
Assignee: Evonik Operations GmbH (Essen, Germany)
Feb. 28, 2023
Retractable Storage Devices
Patent No. 11589679
A retractable storage device for an armrest of a chair, including a vertically extending arm assembly including a first distal end and a second distal end, a horizontally extending arm assembly including a first distal end and a second distal end, a middle connector, and a storage container. The second distal end of the vertically extending arm assembly is pivotally secured to the middle connector, and the first distal end of the horizontally extending arm assembly is pivotally secured to the middle connector. The retractable storage device is moveable between a stowed position and a raised position. The storage container is coupled to the second distal end of the horizontally extending arm assembly, where the storage container is stowed beneath the armrest when the retractable storage device is moved to the stowed position.
Inventors: Jeff E. Dusek (Arlington, Mass.); Adrian F. G. Botran (Key Biscayne, Fla.); Alison A. Palmer (Henrico, Va.); Sabrina Tamames (Key Biscayne, Fla.); Colleen L. Casey (Grapevine, Texas); Riley F. Keen (Plano, Texas); David G. Walter (Aubrey, Texas)
Assignee: Toyota Motor North America (Plano, Texas)
Feb. 28, 2028
System and Method for Facilitating Account Provisioning
Patent No. 11587053
In a method for broadcasting account provisioning information, user datum encryption information is transmitted to a plurality of account processing systems. A request to share account provisioning information is received from a user device associated with an account holder. A user datum of the account holder is encrypted using the encryption information and transmitted to the account processing systems. A response is received from at least one of the account processing systems, the response including an indication that the account holder has a transaction account processed by that account processing system. A request for confirmation that the account provisioning information should be shared is sent to the user device and a confirmation response is received from the user device that includes permission to share account provisioning information. Account provisioning information is then transmitted to one or more of the account processing systems.
Inventors: Jackson Macomber (Henrico, Va.); Kevin Osborn (Newton Highlands, Mass.); Jeffrey Rule (Chevy Chase, Md.)
Assignee: Capital One Services (McLean, Va.)
Feb. 21, 2023
Devices, Systems And Methods For Medicament Delivery
Patent No. 11590286
A method includes moving an actuation lock of a medical injector from a first position to a second position. The actuation lock has an extended portion disposed between a shoulder of a housing and the base when the actuation lock is in the first position. The extended portion is spaced apart from the base when the actuation lock is in the second position. A distal end portion of a base, which is movably coupled to an end portion of the housing, is placed into contact with a body. The base is actuated after the placing to release an energy from an energy storage member within the housing to produce a force to move a needle from a first needle position to a second needle position. At least a portion of the needle extends through the base when the needle is in the second needle position.
Inventors: Eric S. Edwards (Moseley, Va.); Evan T. Edwards (Charlottesville, Va.); Mark J. Licata (Doswell, Va.); Paul F. Meyers (Fishers, Ind.)
Assignee: kaleo (Richmond)
Feb. 28, 2023
Aerosol-generating System Having A Cartridge And A Bypass Air Inlet
Patent No. 11590302
An aerosol-generating system (includes a cartridge, a liquid aerosol-forming substrate, and an aerosol-generating device. The cartridge includes a cartridge housing and a solid aerosol-forming substrate. The aerosol-generating device includes a cavity configured to receive at least a portion of the cartridge, an airflow inlet, and an airflow sensor. The airflow sensor is in fluid communication with the airflow inlet and the cavity). The aerosol-generating device includes a bypass air inlet in fluid communication with the cavity, an electric heater configured to heat the liquid aerosol-forming substrate, a power supply, and a controller. The aerosol-generating system is configured so that the cartridge housing substantially prevents airflow through the bypass air inlet when the cartridge is received within the cavity.
Inventors: Tony Reevell (London, Great Britain)
Assignee: Altria Client Services (Richmond)
Feb. 28, 2023
Nanoparticle Conjugated Synthetic Opioid Prodrugs And Methods Of Their Uses
Patent No. 11590241
Provided herein are nanoparticle conjugated synthetic opioid prodrugs that target the peripheral mu opioid receptor (MOR). The prodrugs exhibit long-lived bioavailability, do not compromise the analgesic effects of opioids administered for pain relief (and in some cases can be used for pain relief), and do not induce opioid withdrawal symptoms, when their use is discontinued. Certain of the prodrugs are especially useful for the prevention and/or treatment of unwanted opioid-induced side effects such as opioid-induced constipation (OIC).
Inventors: Yan Zhang (Glen Allen, Va.); Hu Yang (Richmond); Dana Selley (Richmond); William Dewey (Richmond); Hamid Akbarali (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Feb. 28, 2023
Acetaminophen Formulation With Protection Against Toxic Effects Of Overdose
Patent No. 11590090
An oral pharmaceutical dosage form that comprises both acetaminophen and a glutathione replenishing agent, such as N-acetylcysteine. This allows co-administering the glutathione replenishing agent along with acetaminophen, which may be beneficial in rapidly counteracting the toxic effects of acetaminophen overdose. The oral dosage form could be in the form of a tablet or capsule. The dosage form may be designed to compartmentally separate the glutathione replenishing agent from having chemical interaction with the acetaminophen. The dosage form may be designed to mask the taste or smell of the glutathione replenishing agent.
Inventors: Kevin M. Strait (Ashland, Va.); Daniel J. Strait (Prescott Valley, Ariz.); Cameron D. Kawato (Chesapeake, Va.)
Assignee: Anzen Pharmaceuticals (Ashland, Va.)
Feb. 28, 2028
Systems And Methods For Synchronization Of Photons Over Quantum Channels With Co-propagating Clock Pulses
Patent No. 11588613
Systems and methods for operating a quantum network system. The methods comprise, by a network node: generating optical clock pulses and photons using the optical clock pulses; generating a combined signal by combining the optical clock pulses with at least some of the photons such that a consistent temporal offset exits between the optical clock pulses and the first photons and/or a wave function of each photon at least partially overlaps an envelope of a respective one of the optical clock pulses; and transmitting the combined signal over a first quantum channel in which the optical clock pulses co-propagate with the photons.
Inventors: Michael C. Garrett (Melbourne, Fla.); James A. Nagel (Fort Wayne, Ind.); Victor G. Bucklew (Richmond); Samuel H. Knarr (Melbourne, Fla.); Cypryan T. Klish (Melbourne, Fla.); Timothy C. Burt (Webster, N.Y.)
Assignee: Eagle Technology (Melbourne, Fla.)
Feb. 21, 2023
Helmet Stabilization Apparatus
Patent No. 11583025
A helmet stabilization system and apparatus for reducing the incidence of whiplash and neck injuries while wearing a helmet, such as in contact sports. The invention includes a helmet mount; a base mount configured for attachment to a shoulder harness; and a flex rod interconnectable between the helmet mount and the base mount. The flex rod, when interconnected between the helmet mount and the base mount provides a resistance to an extension or a compression sequence responsive to a contact imparted on the helmet. An oobleck may be provided in a coupling between the flex rod and the base mount to permit voluntary head movements of the user and to provide a resistance responsive to an impact force.
Inventors: Howard Donal Peace III (Richmond)
Assignee: N/A
Feb. 21, 2023
E-vapor Device Including A Compound Heater Structure
Patent No. 11589427
An e-vapor device may include a pre-vapor sector and a heater structure arranged in thermal contact with the pre-vapor sector. The pre-vapor sector includes a reservoir and a dispensing interface. The pre-vapor sector is configured to hold and dispense a pre-vapor formulation. The heater structure is configured to vaporize the pre-vapor formulation to generate a vapor. The heater structure includes a base wire and a heater wire coiled around the base wire. The base wire is insulated from the heater wire. As a result of the heater design, the heater structure is stiffer and more robust than other related heaters in the art, thus allowing more options for its implementation.
Inventors: Peter Lipowicz (Midlothian, Va.)
Assignee: Altria Client Services (Richmond)
Feb. 21, 2023
Radiolucent, 3-D Printed Soft Tissue Retractor
Patent No. 11583268
A radiolucent, 3-D printed soft tissue retractor includes an elongate, curved support body having a long central axis that exceeds the length of a short, transverse axis. A bone engaging concavity is provided on a first side of the body. A concave soft tissue retracting surface is provided on a second side of the body. An inflection point is provided on the body in between the bone engaging concavity and the soft tissue retracting surface. The soft tissue retractor is configured to cooperate with a second soft tissue retractor and a backing plate to retract tissue and stabilize bones during a surgical distal radius fracture repair.
Assignee: Alidad Ghiassi (Los Angeles, Calif.); Steven Howard (La Jolla, Calif.); Bradley Klos (Solana Beach, Calif.); Michael Bauschard (Richmond)
Assignee: Retractortho (Solana Beach, Calif.)
Feb. 21, 2023
Polymeric Surfactants For Improved Emulsion And Flow Properties At Low Temperatures
Patent No. 11584898
A polymer surfactant for improving engine oil emulsion properties of a lubricating composition mixed with water and/or fuel contamination, particularly at very cold temperatures, is described herein. In approaches, selected polymeric and functionalized compounds can impart both robust emulsion properties and simultaneously deliver good low temperature fluidity for lubricating compositions that may contain residual amounts of water and/or fuel contamination. Lubricating compositions including such surfactants demonstrate robust properties at temperatures down to about −30° C.
Assignee: Yunhai Bai (Richmond); Joseph Remias (Glen Allen, Va.); Yen Tran (Richmond); Amy M. James (Richmond); Kristi Engelman (Richmond)
Assignee: Afton Chemical Corp.
Feb. 21, 2023
Cartridge For An Aerosol-generating System With Customizable Identification Resistance
Patent No. 11589429
In a method of manufacturing a cartridge of an electronic vaping device, wherein the cartridge includes a pre-vapor formulation storage element, an electrical resistor is physically manipulated to change a resistance of the electrical resistor from a first resistance value to a second resistance value, the second resistance value indicative of a pre-vapor formulation substrate contained in the pre-vapor formulation storage element. The electrical resistor is then mounted to a portion of the cartridge.
Assignee: Tony Reevell (London, Great Britain)
Assignee: Altria Client Services (Richmond)
Feb. 21, 2023
Lubricant Formulations With Silicon-containing Compounds
Patent No. 11584897
A lubricating oil composition including a major amount of a base oil, one or more calcium-containing detergents to provide at least 1000 ppmw of calcium, and one or more silicon-containing compound(s) to provide at least 50 ppmw of silicon to the lubricating oil composition, all based on the total weight of the lubricating oil composition, wherein a ratio of ppmw of silicon provided by the one or more silicon-containing compound(s) to the lubricating oil composition to the ppmw of calcium provided by the one or more calcium-containing detergent(s) to the lubricating oil composition is from 0.02 to 1. Methods of using these compositions and silicon-containing detergents are also described.
Inventors: Ashutosh Gupta (Henrico, Va.); Ian Bell (Abingdon, Va.); Kongsheng Yang (Glen Allen, Va.); Alexei Neverov (Chesterfield, Va.); Joseph W. Roos (Mechanicsville, Va.); Joseph Remias (Glen Allen, Va.)
Assignee: Afton Chemical Corp. (Richmond)
Feb. 21, 2023
Collar For A Disposable Surgical Gown
Patent No. 11583013
A collar for a disposable surgical gown is provided. The collar includes a first portion having a first end and second end and a second portion having a first and second end. The first ends of the first portion and the second portion meet at a front of the collar to form a v-neck shape and the second ends of the first portion and the second portion meet at a rear of the collar to define a neck opening. The v-neck shape at the front of the collar forms an angle of greater than 90° at the neck opening, while the second end of the first portion and the second end of the second portion are tapered at the rear of the collar. Such an arrangement prevents the collar from gapping when a wearer leans forward or moves during, for instance, a surgical procedure.
Inventors: Jerald T. Jascomb (Roswell, Ga.)
Assignee: O&M Halyard (Mechanicsville, Va.)
Feb. 21, 2023
Cut And Seal Method And Apparatus
Patent No. 11591128
A fin sealer and method to seal a radially outwardly directed fin of a tubular web structure by directing the fin through a nip between a first and a second fin sealing rollers while communicating heat to the fin through at least one of the fin sealing rollers is provided. The fin sealer is configured to maintain a nominal face-to-face relation between an outer annulus of the first fin sealing roller and an outer annulus of the second fin sealing roller with a flexible connection between a hub element of the second fin sealing roller with the outer annulus of the second fin sealing roller.
Inventors: Jarrod W. Chalkley (Mechanicsville, Va.); James D. Evans (Chesterfield, Va.); Thien Hoang Nguyen (Glen Allen, Va.); Patrick s. McElhinney (Chesterfield, Va.)
Assignee: Altria Client Services (Richmond)
Feb. 28, 2023
Multi-layer Visor System For Surgical Hood
Patent No. 11589633
A multi-layer visor system for a surgical hood or garment is provided. The system includes a base film layer and one or more removable film layers that are coextruded at high temperature to form a sterile surface between each of the film layers should the surgeon elect to peel away a soiled or splattered removable film layer during the course of a surgical procedure so that an unobstructed view can be maintained. Thus, no separate sterilization step is required in order to sterilize the layers of the visor system. Each of the removable film layers can additionally include a tab having distinctive features in order to enable a wearer to easily distinguish between the tabs in order to make it easier for a wearer to know which tab to pull first to remove the outermost removable film layer. Further, because the tabs are located about the perimeter of the removable films, viewing is not obscured, yet the film layers are held securely in place until easily removed from the underlying removable film layer or base film layer.
Inventors: Jerald T. Jascomb (Roswell, Ga.); Namita A. Mithani (Alpharetta, Ga.)
Assignee: O&M Halyard (Mechanicalsville, Va.)
Feb. 28, 2023
Biodegradable Cleaning Composition
Patent No. 11591547
The present invention is directed to biodegradable cleaning compositions, in particular hard surface cleaning compositions, and their use. The compositions according to the invention comprise one or more biosurfactants(s), one or more sorbitan ester(s) and one or more further surfactant(s), which is/are neither a biosurfactant nor a sorbitan ester.
Inventors: Zheng Xue (Henrico, Va.); Andras Nagy (Chester, Va.); Dennis Parrish (Sandston, Va.); Sam Christy (Selbyville, Del.); Jennifer Goodyear (Chester, Va.); Jeff Davidson (Beaverdam, Va.)
Assignee: Evonik Operations GmbH (Essen, Germany)
Feb. 28, 2023
Retractable Storage Devices
Patent No. 11589679
A retractable storage device for an armrest of a chair, including a vertically extending arm assembly including a first distal end and a second distal end, a horizontally extending arm assembly including a first distal end and a second distal end, a middle connector, and a storage container. The second distal end of the vertically extending arm assembly is pivotally secured to the middle connector, and the first distal end of the horizontally extending arm assembly is pivotally secured to the middle connector. The retractable storage device is moveable between a stowed position and a raised position. The storage container is coupled to the second distal end of the horizontally extending arm assembly, where the storage container is stowed beneath the armrest when the retractable storage device is moved to the stowed position.
Inventors: Jeff E. Dusek (Arlington, Mass.); Adrian F. G. Botran (Key Biscayne, Fla.); Alison A. Palmer (Henrico, Va.); Sabrina Tamames (Key Biscayne, Fla.); Colleen L. Casey (Grapevine, Texas); Riley F. Keen (Plano, Texas); David G. Walter (Aubrey, Texas)
Assignee: Toyota Motor North America (Plano, Texas)
Feb. 28, 2028
System and Method for Facilitating Account Provisioning
Patent No. 11587053
In a method for broadcasting account provisioning information, user datum encryption information is transmitted to a plurality of account processing systems. A request to share account provisioning information is received from a user device associated with an account holder. A user datum of the account holder is encrypted using the encryption information and transmitted to the account processing systems. A response is received from at least one of the account processing systems, the response including an indication that the account holder has a transaction account processed by that account processing system. A request for confirmation that the account provisioning information should be shared is sent to the user device and a confirmation response is received from the user device that includes permission to share account provisioning information. Account provisioning information is then transmitted to one or more of the account processing systems.
Inventors: Jackson Macomber (Henrico, Va.); Kevin Osborn (Newton Highlands, Mass.); Jeffrey Rule (Chevy Chase, Md.)
Assignee: Capital One Services (McLean, Va.)
Feb. 21, 2023
Devices, Systems And Methods For Medicament Delivery
Patent No. 11590286
A method includes moving an actuation lock of a medical injector from a first position to a second position. The actuation lock has an extended portion disposed between a shoulder of a housing and the base when the actuation lock is in the first position. The extended portion is spaced apart from the base when the actuation lock is in the second position. A distal end portion of a base, which is movably coupled to an end portion of the housing, is placed into contact with a body. The base is actuated after the placing to release an energy from an energy storage member within the housing to produce a force to move a needle from a first needle position to a second needle position. At least a portion of the needle extends through the base when the needle is in the second needle position.
Inventors: Eric S. Edwards (Moseley, Va.); Evan T. Edwards (Charlottesville, Va.); Mark J. Licata (Doswell, Va.); Paul F. Meyers (Fishers, Ind.)
Assignee: kaleo (Richmond)
Feb. 28, 2023
Aerosol-generating System Having A Cartridge And A Bypass Air Inlet
Patent No. 11590302
An aerosol-generating system (includes a cartridge, a liquid aerosol-forming substrate, and an aerosol-generating device. The cartridge includes a cartridge housing and a solid aerosol-forming substrate. The aerosol-generating device includes a cavity configured to receive at least a portion of the cartridge, an airflow inlet, and an airflow sensor. The airflow sensor is in fluid communication with the airflow inlet and the cavity). The aerosol-generating device includes a bypass air inlet in fluid communication with the cavity, an electric heater configured to heat the liquid aerosol-forming substrate, a power supply, and a controller. The aerosol-generating system is configured so that the cartridge housing substantially prevents airflow through the bypass air inlet when the cartridge is received within the cavity.
Inventors: Tony Reevell (London, Great Britain)
Assignee: Altria Client Services (Richmond)
Feb. 28, 2023
Nanoparticle Conjugated Synthetic Opioid Prodrugs And Methods Of Their Uses
Patent No. 11590241
Provided herein are nanoparticle conjugated synthetic opioid prodrugs that target the peripheral mu opioid receptor (MOR). The prodrugs exhibit long-lived bioavailability, do not compromise the analgesic effects of opioids administered for pain relief (and in some cases can be used for pain relief), and do not induce opioid withdrawal symptoms, when their use is discontinued. Certain of the prodrugs are especially useful for the prevention and/or treatment of unwanted opioid-induced side effects such as opioid-induced constipation (OIC).
Inventors: Yan Zhang (Glen Allen, Va.); Hu Yang (Richmond); Dana Selley (Richmond); William Dewey (Richmond); Hamid Akbarali (Richmond)
Assignee: Virginia Commonwealth University (Richmond)
Feb. 28, 2023
Acetaminophen Formulation With Protection Against Toxic Effects Of Overdose
Patent No. 11590090
An oral pharmaceutical dosage form that comprises both acetaminophen and a glutathione replenishing agent, such as N-acetylcysteine. This allows co-administering the glutathione replenishing agent along with acetaminophen, which may be beneficial in rapidly counteracting the toxic effects of acetaminophen overdose. The oral dosage form could be in the form of a tablet or capsule. The dosage form may be designed to compartmentally separate the glutathione replenishing agent from having chemical interaction with the acetaminophen. The dosage form may be designed to mask the taste or smell of the glutathione replenishing agent.
Inventors: Kevin M. Strait (Ashland, Va.); Daniel J. Strait (Prescott Valley, Ariz.); Cameron D. Kawato (Chesapeake, Va.)
Assignee: Anzen Pharmaceuticals (Ashland, Va.)
Feb. 28, 2028